| 李丽娟,黎庶.三阴乳腺癌与非三阴乳腺癌X线及病理特征分析[J].中国医学影像技术,2012,28(11):2015~2018 |
| 三阴乳腺癌与非三阴乳腺癌X线及病理特征分析 |
| Mammographic features and histopathological characteristics of triple negative breast cancer and non-triple negative breast cancer |
| 投稿时间：2012-06-05 修订日期：2012-08-08 |
| DOI： |
| 中文关键词: 乳腺肿瘤 乳房X线摄影术 免疫组织化学 |
| 英文关键词:Breast neoplasms Mammography Immunohistochemistry |
| 基金项目: |
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| 摘要点击次数: 1768 |
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| 中文摘要: |
| 目的 与非三阴乳腺癌(non-TNBC)比较,探讨三阴乳腺癌(TNBC)的X线表现及病理特征。 方法 回顾性分析经病理证实的574例乳腺癌患者资料,对比分析81例TNBC(TNBC组)与493例non-TNBC患者(non-TNBC组)的临床、病理特征及X线表现。 结果 TNBC组织学分级以中、高级别为主,其中53.09%(43/81)发生腋窝淋巴结转移,高于non-TNBC组(39.96%,197/493,P<0.05)。与non-TNBC组相比,TNBC病变体积较大,多为单纯肿块型,少见钙化(P<0.05),肿块型TNBC瘤体多为类圆形,边缘光滑,较少见不规则形及毛刺(P<0.05)。 结论 TNBC与non-TNBC在X线表现及病理特征方面存在一定差异,了解其特征有助于诊断TNBC。 |
| 英文摘要: |
| Objective To explore the mammographic features and histpathological characteristics of triple negative breast cancer (TNBC) compared with non-triple negative breast cancer (non-TNBC). Methods A total of 574 patients with histopathologically confirmed breast cancer were analyzed retrospectively. The clinical, histopathological and mammographic imaging characteristics of TNBC patients (n=81) were analyzed and compared with those of non-TNBC patients (n=493). Results Most of TNBC showed intermediate and high histological grade. The percentage of lymph node metastasis in TNBC group (43/81, 53.09%) was higher than that of non-TNBC group (197/493, 39.96%, P<0.05). Tumors in TNBC group were larger than non-TNBC group, usually presented as a mass with less calcifications (P<0.05). The masses of TNBC frequently presented as oval and smooth margin, with less irregular and burr (P<0.05). Conclusion There are some differences between TNBC and non-TNBC in pathology and radiology. Understanding these characters might be useful to diagnose TNBC. |
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