马春燕,刘爽,杨军,张妍,马少卫,于波,唐力.组织多普勒成像评价心脏再同步化治疗对右心室功能和同步性的短期影响[J].中国医学影像技术,2012,28(11):1990~1993
组织多普勒成像评价心脏再同步化治疗对右心室功能和同步性的短期影响
Short-effect of cardiac resynchronization therapy on right ventricular systolic function and synchrony with tissue Doppler imaging
投稿时间:2012-05-31  修订日期:2012-06-29
DOI:
中文关键词:  再同步化治疗  组织多普勒成像  心室功能,右  同步性
英文关键词:Cardiac resynchronization therapy  Tissue Doppler imaging  Ventricular function, right  Synchrony
基金项目:辽宁省自然科学基金(20102280)。
作者单位E-mail
马春燕 中国医科大学附属第一医院心血管超声科,辽宁 沈阳 110001 mcy_ql@yahoo.com.cn 
刘爽 中国医科大学附属第一医院心血管超声科,辽宁 沈阳 110001  
杨军 中国医科大学附属第一医院心血管超声科,辽宁 沈阳 110001  
张妍 中国医科大学附属第一医院心血管超声科,辽宁 沈阳 110001  
马少卫 中国医科大学附属第一医院心内科,辽宁 沈阳 110001  
于波 中国医科大学附属第一医院心内科,辽宁 沈阳 110001  
唐力 中国医科大学附属第一医院心血管超声科,辽宁 沈阳 110001  
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中文摘要:
      目的 采用TDI评价心脏再同步化治疗(CRT)对右心室(RV)收缩功能和同步性的短期影响。 方法 对51例因慢性心力衰竭(CHF)而接受CRT治疗的患者,于术前和术后1个月行常规超声心动图和TDI检查,检测右心室内径(RVD)、游离壁收缩期峰值速度(RVv)和同步性(RV-T),同时检测左心室收缩末期容积(LVESV)、射血分数(LVEF)和同步性(LV-TSD)。以术后1个月LVESV减小率ΔLVESV≥15%为CRT治疗有效,比较术后与术前各参数的变化。 结果 CRT术后38例患者(38/51,74.51%)为有效组,13例(13/51,25.49%)为无效组。两组术后RVD无变化,右心室收缩功能(RVv)和同步性(RV-T)均显著改善,RVv改善率与术前RVv和RV-T密切相关(r=0.69、-0.73,P<0.05),而与LV-TSD无相关。 结论 短期CRT即可显著改善右心室收缩功能和同步性。
英文摘要:
      Objective To assess the short-effect of cardiac resynchronization therapy (CRT) on right ventricular (RV) systolic function and synchrony with TDI. Methods Fifty-one heart failure patients underwent conventional ultrasonography and TDI examination before and 1 month after CRT. RV dimension (RVD), lateral wall tissue velocity (RVv) and RV dyssynchrony (RV-T) were detected. Meantime, left ventricular end-systolic volume (LVESV), left ventricular ejection fraction (LVEF), and dyssynchrony (LV-TSD) were assessed. Patients with reduction ≥15% in LVESV 1 month after CRT were classified as responders. Parameters were compared between preoperation and postoperation. Results Thirty-eight patients (38/51, 74.51%) were classified as responders, and 13 were classified as non-responders (13/51, 25.49%). RVD did not change, but RVv and RV-T increased significantly in both responders and non-responders after CRT. And the improvement of RVv correlated with RVv and RV-T before CRT (r=0.69, -0.73, P<0.05), while did not correlate with LV-TSD. Conclusion CRT can promptly increase the RV systolic function and synchrony in short time.
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