| 鲁雪红,肖虎,刘文亚,刘晓蓓.宫颈癌大小和病理分化程度与ADC值的相关性[J].中国医学影像技术,2012,28(10):1882~1885 |
| 宫颈癌大小和病理分化程度与ADC值的相关性 |
| Correlation of size and pathological grading of cervical carcinoma with ADC values |
| 投稿时间：2012-03-19 修订日期：2012-09-03 |
| DOI： |
| 中文关键词: 子宫颈肿瘤 扩散磁共振成像 肿瘤分期 |
| 英文关键词:Uterine cervical neoplasms Diffusion magnetic resonance imaging Neoplasm staging |
| 基金项目:新疆维吾尔自治区科技厅自然科学基金(2009211A13)。 |
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| 中文摘要: |
| 目的 探讨宫颈癌癌灶大小及病理分化程度与ADC值的关系。方法 收集确诊为宫颈癌的患者53例,均于治疗前接受常规MR及DWI检查,b=1000 s/mm2,记录其病理类型、分化程度。采用后处理工作站的像素分析软件划定ROI,测量肿瘤ADC值和大小,并分析相互间的关系。结果 肿瘤平均ADC值为(1.05±0.17)×10-3mm2/s,与病灶横断面最大径(r=-0.28,P=0.04)及体积(r=-0.40,P<0.01)均呈负相关;不同分化程度的宫颈癌病灶横断面最大径、体积及ADC值间差异均无统计学意义(P均>0.05)。结论 宫颈癌病灶体积越大,ADC值越趋向于低;而ADC值及体积大小均不能反映肿瘤的分化程度。 |
| 英文摘要: |
| Objective To evaluate the correlation of size and pathological grading of cervical carcinoma with ADC values. Methods Totally 53 patients with pathologically proved cervical carcinoma were included and underwent routine MRI and DWI (b=1000 s/mm2) before therapy. The size and pathological type of tumors were recorded. Analysis and measurement of DWI were performed on postprocess workstation with a pixel-analysis software. ADC value and tumor size were measured, and their correlation was analyzed. Results The mean ADC value of cervical carcinoma was (1.05±0.17)×10-3mm2/s. There was negative correlation between ADC values and maximum axial diameter (r=-0.28, P=0.04), as well as tumor volume (r=-0.40, P<0.01). There was no significant difference in ADC values, maximal axial diameter and tumor volume among different grades of cervical carcinoma (all P>0.05). Conclusion There is a tendency that the ADC value decreases while the tumor volume increases. Neither the ADC values nor size can indicate pathological grading of cervical carcinoma. |
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