| 李淑静,孙舰,郭欣珊,王藏海,史朝霞.特发性肺纤维化薄层MSCT征象与肺功能的相关性[J].中国医学影像技术,2012,28(10):1844~1847 |
| 特发性肺纤维化薄层MSCT征象与肺功能的相关性 |
| Idiopathic pulmonary fibrosis: Correlation between thin-section MSCT findings and pulmonary function test results |
| 投稿时间：2012-05-10 修订日期：2012-06-15 |
| DOI： |
| 中文关键词: 特发性肺纤维化 体层摄影术,X线计算机 肺功能测试 相关性分析 |
| 英文关键词:Idiopathic pulmonary fibrosis Tomography, X-ray computed Pulmonary function tests Correlative analysis |
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| 中文摘要: |
| 目的 探讨特发性肺纤维化(IPF)薄层MSCT表现特征与肺功能检查诸项指标之间的相关性。方法 对临床病理证实的IPF患者30例行薄层MSCT扫描,观察薄层MSCT征象及其解剖分布,对薄预定层面的各征象累及范围进行评分统计。对薄层MSCT各征象与肺功能诸项指标进行相关性分析。结果 30例IPF患者均表现为限制性通气功能障碍。薄层MSCT各征象总的半定量评分与肺活量(VC)、肺总量(TLC)、残气量、用力肺活量、第1秒用力呼气容积、肺一氧化碳弥散量和弥散常数均呈负相关(r=-0.646、-0.661、-0.415、-0.624、-0.483、-0.732、-0.504,P均<0.05),与限制性通气功能分级和弥散功能分级之间呈正相关(r=0.843、0.838,P均<0.001)。VC、TLC与网织影、蜂窝肺呈负相关(r=-0.621、-0.688、-0.387、-0.456,P均<0.05)。结论 IPF薄层MSCT半定量评分与肺功能之间存在较强相关性,分析薄层MSCT征象有助于预测肺功能。 |
| 英文摘要: |
| Objective To assess the correlation between thin-section MSCT findings and pulmonary function test results of idiopathic pulmonary fibrosis (IPF). Methods Thirty patients with clinically and/or pathologically proved IPF underwent thin-section MSCT. The presence and anatomic distribution of thin-section MSCT were assessed, and the extent of abnormal parenchyma was scored at pre-selected levels. The correlation between thin-section MSCT score and the values of pulmonary function tests was examined. Results The pulmonary function tests revealed restrictive ventilatory defect in all the patients. The total scores in thin-section CT negatively correlated with vital capacity (VC), total lung capacity (TLC), residual volume, forced inspiratory vital capacity, forced expiratory volume in one second, DLCO and DLCO/VA (r=-0.646, -0.661, -0.415, -0.624, -0.483, -0.732,-0.504, all P<0.05), positively correlated with degrees of restricted ventilation function disturbance and diffuse function changes the lung (r=0.843, 0.838, all P<0.001), while VC, TLC negatively correlated with reticular structures and honeycombing (r=-0.621, -0.688, -0.387, -0.456, all P<0.05). Conclusion Thin-section MSCT can provide significant information for assessment of pathologic severity of idiopathic pulmonary fibrosis. There is good correlation between thin-section MSCT findings and pulmonary function tests results. |
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