刘影,麻苏培,邹丽丽,王凯,马军.富于淋巴浆细胞型脑膜瘤的影像学与病理特征[J].中国医学影像技术,2012,28(8):1488~1492
富于淋巴浆细胞型脑膜瘤的影像学与病理特征
Imaging and pathological characteristics of lymphoplasmacyte-rich meningioma
投稿时间:2012-02-20  修订日期:2012-04-27
DOI:
中文关键词:  富于淋巴浆细胞型脑膜瘤  体层摄影术,X线计算机  磁共振成像  病理学
英文关键词:Lymphoplasmacyte-rich meningioma  Tomography, X-ray computed  Magnetic resonance imaging  Pathology
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作者单位E-mail
刘影 首都医科大学附属北京天坛医院神经影像中心, 北京 100050  
麻苏培 首都医科大学附属北京天坛医院神经影像中心, 北京 100050  
邹丽丽 首都医科大学附属北京天坛医院神经影像中心, 北京 100050  
王凯 首都医科大学附属北京天坛医院神经影像中心, 北京 100050  
马军 首都医科大学附属北京天坛医院神经影像中心, 北京 100050 dr_ma@sina.com 
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中文摘要:
      目的 分析富于淋巴浆细胞型脑膜瘤(LPRM)的影像学特征和病理表现。方法 回顾性分析8例经手术病理证实的LPRM患者的CT、MR和临床病理资料。结果 8例患者中,病变发生在大脑半球表面3例,大脑镰旁1例,鞍上2例,3脑室后1例,侧裂池1例;其中7例为单发,1例多发。4例接受CT平扫,其中2例病灶密度均匀,1例内部可见坏死灶,1例可见出血液化灶。8例均接受MR扫描,T1WI均呈等或稍低信号,T2WI 6例呈稍高信号,2例为低信号。1例病变内部可见T1WI低信号、T2WI高信号坏死区,1例可见高信号出血灶。增强后5例病变明显均匀强化,3例不均匀强化。2例可见脑膜尾征。光镜下可见大量淋巴细胞、浆细胞背景下,脑膜上皮细胞以不同形状排列。结论 LPRM具有脑膜瘤的一般影像学特点,同时具有独特表现,结合病理有助于临床诊断及鉴别。
英文摘要:
      Objective To analyze the imaging and pathological features of lymphoplasmacyte-rich meningioma (LPRM). Methods The imaging and pathological data of 8 patients with LPRM were reviewed. Results The lesions located in convexity of cerebral hemisphere in 3 cases, in parafalx in 1 case, in the suprasellar region in 2 cases, in the posterior of the third ventricle in 1 case, while in the sylvius fissure in 1 case. LPRM in 7 cases were solitary, in 1 case were multiple lesions. Four patients received conventional CT examination. The lesions showed homogeneous density in CT in 2 cases, while necrosis was found as low density in 1 case and hemorrhage was detected in 1 case as low density focus. All cases received MR examination, the lesions showed hypo-isointense on T1WI, slight hyperintense in 6 and hypointense in 2 cases on T2WI. Necrosis happened in 1 case presenting as hypointense on T1WI and hyperintense on T2WI, while hemorrhage happened in 1 case presenting as hyperintense on MRI. After contrast injection, homogeneous enhancement was noticed in 5 cases on MRI, while heterogeneous enhancement was found in 3 cases, and dural "tail sign" was found in 2 cases. Pathological results showed infiltration of a great quantity of lymphoplasmacytes and irregular arrangement of the meningeal epithelial cells. Conclusion LPRM has not only common imaging characteristics of general meningiomas, but also some features of its own. Combination of imaging and pathological findings is helpful to the diagnosis and differential diagnosis of this disease.
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