田志辉,王琦,时高峰,曹彦坤.双能CT测定体模碘含量[J].中国医学影像技术,2012,28(7):1406~1410
双能CT测定体模碘含量
Dual energy CT measurement of iodine concentration in a phantom
投稿时间:2011-08-18  修订日期:2012-01-19
DOI:
中文关键词:  碘含量  体层摄影术,X线计算机  对比研究
英文关键词:Iodine-containing  Tomography, X-ray computed  Compared study
基金项目:河北省卫生厅科研基金项目(20110134)。
作者单位E-mail
田志辉 河北医科大学第四医院CT室, 河北 石家庄 050011  
王琦 河北医科大学第四医院CT室, 河北 石家庄 050011  
时高峰 河北医科大学第四医院CT室, 河北 石家庄 050011 gaofengs62@sina.com 
曹彦坤 河北医科大学第四医院放疗科, 河北 石家庄 050011  
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中文摘要:
      目的 利用体模验证双能CT碘含量测定的可靠性。方法 配置16种不同浓度碘对比剂的试管放置于体模中,浓度梯度为0、0.1、0.3、0.5、0.7、0.9、1.0、2.0……10.0(mg/ml)。采用两种能量模式进行双能CT扫描,管电压分别为80、140 kV和100、140 kV。分为4组处理对象:80、140 kV,5 mm重建层厚组(A组);100、140 kV,5 mm重建层厚组(B组);80、140 kV,1 mm重建层厚组(C组);100、140 kV,1 mm重建层厚组(D组)。采用方差分析和Pearson相关分析比较真实值与测量值。结果 4组碘测量值与真实碘含量之间均具有明显相关性(r=0.999)。4组测量值与真实值间差异无统计学意义(P=0.998)。试管的CT值在4组间差异无统计学意义(P=0.860);随试管内碘浓度逐渐增高,CT值测量受扫描电压影响出现偏移。单能量曲线显示试管的CT值随能量的增加而减小。结论 双源CT定量分析不同浓度溶液碘含量的准确性较高。
英文摘要:
      Objective To validate the utility of dual-source dual energy CT in quantifying iodine concentration in a phantom. Methods Non-ionic contrast iodine dispersed with distilled water were filled into 16 test tubes with concentration of 0, 0.1, 0.3, 0.5, 0.7, 0.9, 1.0, 2.0……10.0 (mg/ml), and the tubes were placed into the phantom. Dual-source dual-energy CT scanning of the phantom was performed using two kinds of scan voltage, i.e. method 1 (tube A, 80 kV; tube B, 140 kV) and method 2 (tube A, 100 kV; tube B, 140 kV), respectively. There were 4 groups: group A, 80, 140 kV and 5 mm reconstruction slice thickness, group B, 100,140 kV and 5 mm, group C, 80, 140 kV and 1 mm, group D, 100, 140 kV and 1 mm. Analysis of variance and Pearson correlation analysis were used to compare the calculated outcomes with known iodine concentration. Results The iodine measurements in all groups positively correlated to the real values of the ion (r=0.999). No significant difference was found between the calculated and true iodine concentration (P=0.998). CT values were not statistically different among 4 groups (P=0.860). CT values of high concentration tubes showed warp with different scan voltage. The curve of monochromatic imaging of spectral CT showed that CT values dropped off with the gradual increase of monochromatic energy. Conclusion Dual-source CT has good accuracy in the material composition analysis of different concentrations of iodine solution.
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