邝菲,陈自谦,钟群,付丽媛.不同b值联合诊断宫颈病变的价值[J].中国医学影像技术,2012,28(6):1174~1178
不同b值联合诊断宫颈病变的价值
Value of different b-value combinations for the diagnosis of cervical lesions
投稿时间:2011-10-19  修订日期:2012-01-13
DOI:
中文关键词:  宫颈病变  ADC值  诊断,鉴别
英文关键词:Uterine cervical diseases  Apparent diffusion coefficient  Diagnosis, differential
基金项目:
作者单位E-mail
邝菲 中国人民解放军第174医院放射科,福建 厦门 361003  
陈自谦 南京军区福州总医院医学影像科,福建 福州 350025 chenziqian_fuzong@163.com 
钟群 南京军区福州总医院医学影像科,福建 福州 350025  
付丽媛 南京军区福州总医院医学影像科,福建 福州 350025  
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中文摘要:
      目的 探讨不同b值联合鉴别诊断宫颈良恶性病变及正常宫颈组织的价值。方法 采用3.0T MR对106例宫颈癌、8例宫颈肌瘤、12例宫颈癌前期病变Ⅲ(CIN Ⅲ)患者及67名正常对照者进行常规MR、DWI扫描,由b=0、600 s/mm2及b=0、 1000 s/mm2两组ADC图计算ADC值,根据ROC曲线比较两组ADC图评估不同宫颈病变的价值。结果 宫颈癌两组b值的ADC值均低于宫颈肌瘤、CIN Ⅲ及正常宫颈组织(P均<0.001);宫颈肌瘤与CIN Ⅲ、宫颈肌瘤与正常宫颈组织两组b值的ADC值差异均有统计学意义(P均<0.05);在CIN Ⅲ与正常宫颈组织间两组b值的ADC值差异均无统计学意义(P均>0.05)。结论 ADC值对于鉴别宫颈恶性与良性病变及正常宫颈组织有较高价值;两组b值的诊断价值相当。
英文摘要:
      Objective To observe the value of different b-value combinations for the diagnosis of malignant and benign lesions or normal cervical tissues. Methods Totally 106 patients with cervical cancer, 8 with cervical leiomyoma, 12 with cervical intraepithelial neoplasia Ⅲ (CIN Ⅲ) and 67 normal controls underwent MR and DWI scan. All ADCs were calculated with b=0, 600 s/mm2 and b=0, 1000 s/mm2. Results ADCs of cervical cancer were significantly lower than those of benign lesions or normal cervical tissues at both ADC maps (all P<0.001), and statistical differences were found between cervical leiomyoma and CIN Ⅲ, as well as between leiomyoma and normal cervix at both ADC maps (all P<0.05). There was no significant difference between CIN Ⅲ and normal cervix at both ADC maps (both P>0.05). Conclusion ADC values are reliable in differentiating cervical malignancies from benign lesions or normal cervical tissue with high diagnostic accuracy. The diagnostic accuracy is equal at both ADC maps.
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