| 吴江,朱虹,王新刚,桂一,胡裕效,杨桂芬.淋巴瘤脾脏浸润的18F-FDG PET/CT表现[J].中国医学影像技术,2012,28(6):1157~1160 |
| 淋巴瘤脾脏浸润的18F-FDG PET/CT表现 |
| 18F-FDG PET/CT manifestations of spleen infiltration of lymphoma |
| 投稿时间：2011-09-22 修订日期：2011-11-02 |
| DOI： |
| 中文关键词: 淋巴瘤 脾脏 肿瘤转移 体层摄影术,发射型计算机 体层摄影术,X线计算机 18F 氟脱氧葡萄糖 |
| 英文关键词:Lymphoma Spleen Neoplasm metastasis Tomography, emission-computed Tomography, X-ray computed Fluorodeoxyglucose F18 |
| 基金项目:江苏省自然科学基金(BK2011665)、南京军区南京总医院立项课题(2011024)。 |
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| 中文摘要: |
| 目的 探讨18F-FDG PET/CT在诊断淋巴瘤脾脏浸润中的应用价值。方法 回顾经18F-FDG PET/CT诊断为淋巴瘤脾脏浸润的42例患者,分析脾脏体积、病灶大小、病灶密度、病灶最大标准摄取值(SUVmax)和正常肝脏SUVmax。结果 42例淋巴瘤脾脏浸润的18F-FDG PET/CT表现分为3型,其中Ⅰ型(单纯弥漫型浸润)24例、Ⅱ型(单纯结节型浸润)13例,Ⅲ型(混合型浸润)5例。在淋巴瘤浸润脾脏病灶的SUVmax 中,Ⅱ型、Ⅲ型＞Ⅰ型(P均＜0.05),Ⅱ型与Ⅲ型差异无统计学意义。霍奇金病(HD)与非霍奇金淋巴瘤(NHL)、B细胞淋巴瘤与T细胞/NK细胞淋巴瘤、B细胞淋巴瘤与HD的脾脏浸润PET/CT分型差异均无统计学意义(P=0.07、0.18、0.17);T细胞/NK细胞淋巴瘤与HD的脾脏浸润PET/CT分型差异有统计学意义(P=0.02)。结论 18F-FDG PET/CT诊断脾脏淋巴瘤浸润有明显优势,其表现以Ⅰ型和Ⅱ型为主;淋巴瘤浸润脾脏结节样病灶的18F-FDG摄取显著高于弥漫性病灶;T细胞/NK细胞淋巴瘤累及脾脏较HD更多表现为Ⅰ型。 |
| 英文摘要: |
| Objective To observe the value of 18F-FDG PET/CT in patients with spleen infiltration of lymphoma. Methods Forty-two patients diagnosed as spleen infiltration of lymphoma with 18F-FDG PET/CT were retrospectively analyzed. The spleen volume, size, density, maximal standardized uptake value (SUVmax) of the lesions in the spleen and the liver were analyzed. Results Three types of spleen infiltration were displayed with 18F-FDG PET/CT, including 24 patients of type Ⅰ (pure diffuse infiltration), 13 of type Ⅱ (pure nodular infiltration) and 5 of type Ⅲ (mixed infiltration). SUVmax of splenic lesions in type Ⅱ and type Ⅲ were higher than that of type Ⅰ (both P＜0.05), but there was no statistical difference between type Ⅱ and type Ⅲ. There was no statistical difference about PET/CT performances of spleen infiltration respectively between Hodgkin diseases (HD) and non-Hodgkin lymphoma (NHL), B-cell lymphoma and T-cell/NK-cell lymphoma, nor between B-cell lymphoma and HD (P=0.07, 0.18, 0.17), while significant difference was found between T-cell/NK-cell lymphoma and HD (P=0.02). Conclusion 18F-FDG PET/CT has advantages in diagnosing spleen infiltration of lymphoma, which mainly display as type Ⅰ and type Ⅱ. 18F-FDG uptake of nodular-like lesions was significantly higher than that of diffuse lesions in spleens when involved by lymphoma. Compared with HD, T-cell/NK-cell lymphoma involving spleen mostly showed as type Ⅰ. |
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