| 孙伟,李忱瑞,周纯武.原发性肝癌术后复发影响因素的临床分析[J].中国医学影像技术,2012,28(6):1148~1151 |
| 原发性肝癌术后复发影响因素的临床分析 |
| Clinical analysis of impact factors of hepatocellular carcinoma recurrence in patients after surgical resection |
| 投稿时间：2012-01-29 修订日期：2012-03-10 |
| DOI： |
| 中文关键词: 癌,肝细胞 复发 预后 |
| 英文关键词:Carcinoma, hepatocellular Recurrence Prognosis |
| 基金项目: |
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| 中文摘要: |
| 目的 探讨影响原发性肝细胞癌(HCC)术后复发的因素,为临床综合治疗提供依据。方法 分析2003—2008年于我院接受肿瘤切除术的HCC患者206例,分析患者术后0.5、1、2、3年的累计复发率,同时对可能影响HCC术后复发的因素进行统计学处理,包括患者性别、肝功能分级、肿瘤大小、有无子灶、包膜情况、脉管瘤栓和病理切缘,分析上述因素与肿瘤复发之间的关系。结果 术后0.5、1、2、3年,累计HCC肝内复发率分别为21.36％(44/206)、44.66％(92/206)、73.79％(152/206)、89.32％(184/206)。包膜不完整或缺如对HCC术后复发影响最大(P<0.001),其次为脉管瘤栓、病灶大小和病理切缘阳性(P=0.014、0.019、0.045);病灶越大,对术后复发影响越大。结论 充分评估影响HCC术后复发的风险因素,能够为临床综合治疗提供依据。 |
| 英文摘要: |
| Objective To analyze the impact factors of postoperative recurrence of hepatocellular carcinoma (HCC) in patients after surgical resection of the primary tumor. Methods Totally 206 patients with HCC who underwent surgical resection between 2003 and 2008 were reviewed. The postoperative cumulative recurrent rates at 0.5-, 1-, 2- and 3- year were analyzed respectively. The relationship between impact factors and the recurrence of HCC were also analyzed statistically. The impact factors included sex, liver function, tumor size, satellite nodule, pseudocapsule completion, intravascular cancer embolus and pathological margins. Results The cumulative recurrent rate of 0.5-, 1-, 2- and 3-year was 21.36％ (44/206), 44.66％ (92/206), 73.79％ (152/206) and 89.32％ (184/206), respectively. The most important impact factor was tumor with incomplete or without pseudocapsule (P<0.001), then was intravascular cancer embolus (P=0.014), tumor with large volume (P=0.019), and positive pathological margin (P=0.045). Conclusion Sufficient evaluation on postoperative recurrence risk factors of HCC was very useful for clinical therapy. |
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