| 李苗,郑转梅,姜珏,周琦,雷小莹.对比分析CEUS和ECT诊断良恶性甲状腺低回声结节[J].中国医学影像技术,2012,28(6):1093~1097 |
| 对比分析CEUS和ECT诊断良恶性甲状腺低回声结节 |
| Comparative analysis on CUES and ECT in differential diagnosis of benign and malignant thyroid nodules in low echo level |
| 投稿时间：2011-12-25 修订日期：2012-02-10 |
| DOI： |
| 中文关键词: 超声检查 造影剂 体层摄影术,发射型计算机 甲状腺 结节 |
| 英文关键词:Ultrasonography Contrast media Tomography, emission-computed Thyroid Nodules |
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| 中文摘要: |
| 目的 评价CEUS和ECT在甲状腺低回声结节良恶性中的鉴别诊断价值。方法 对186个确诊的良恶性甲状腺低回声结节行ECT和CEUS,对比两种方法的诊断敏感度、特异度、阳性预测值、阴性预测值及符合率,同时绘制ROC曲线,并比较曲线下面积。结果 186个甲状腺低回声结节,病理诊断良性结节117个,恶性结节69个,良性结节在注射造影剂后以高增强和等增强为主,恶性结节以低增强为主。CEUS诊断甲状腺低回声结节的敏感度、特异度、阳性预测值、阴性预测值和准确率分别为86.96%(60/69)、88.89%(104/117)、82.19%(60/73)、92.04%(104/113)和88.17%(164/186);ECT诊断分别为60.87%(42/69)、78.63%(92/117)、62.69%(42/67)、77.31%(92/119)和72.04%(134/186)。两组间各项指标比较差异均有统计学意义(P均<0.05)。CEUS和ECT诊断甲状腺低回声结节的ROC曲线下面积分别为0.950和0.779,差异有统计学意义(P<0.05)。结论 CEUS较ECT对鉴别诊断良恶性甲状腺低回声结节具有较高价值。 |
| 英文摘要: |
| Objective To assess the value of CEUS and ECT in differential diagnosis of benign and malignant thyroid nodules in low echo level. Methods Totally 186 benign or malignant thyroid nodules verified with pathology in low echo level were comparatively observed by using ECT and CEUS. The diagnostic sensitivity, specificity, positive predictive value, negative predictive value and accordance rate of the two methods were evaluated. Meanwhile, ROC curves were drawn and the areas under the curves were compared. Results Of the 186 nodules, 117 were benign thyroid nodules and 69 were malignant thyroid nodules. Most benign nodules showed hyper or equal enhancement, while most malignant thyroid nodules showed hypo-enhancement. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy rate of CEUS was 86.96% (60/69), 88.89% (104/117), 82.19% (60/73), 92.04% (104/113) and 88.17% (164/186), respectively, while for ECT was 60.87%(42/69), 78.63% (92/117), 62.69% (42/67), 77.31% (92/119) and 72.04% (134/186), respectively. There was statistical difference for each index between the two methods (all P<0.05). The area under ROC curve of the two methods was 0.950 and 0.779, respectively (P<0.05). Conclusion Compared with ECT, CEUS has higher differential diagnosis value of benign and malignant thyroid nodules in low echo level. |
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