| 邝思驰,王劲,胡冰,单鸿.肝移植术后脑桥中央髓鞘溶解症的MRI表现[J].中国医学影像技术,2012,28(6):1072~1075 |
| 肝移植术后脑桥中央髓鞘溶解症的MRI表现 |
| MRI manifestations of central pontine myelinolysis after liver transplantation |
| 投稿时间：2011-10-20 修订日期：2012-01-15 |
| DOI： |
| 中文关键词: 肝移植 髓鞘溶解,中心性脑桥 磁共振成像 |
| 英文关键词:Liver transplantation Myelinolysis, central pontine Magnetic resonance imaging |
| 基金项目: |
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| 中文摘要: |
| 目的 探讨MRI诊断肝移植术后脑桥中央髓鞘溶解症(CPM)的价值。方法 回顾性分析我院7例在肝移植术后接受MR扫描并经临床证实为CPM患者的影像学特征。结果 发现7例患者MRI均在脑桥中央呈"斑片状"、"蝙蝠翅膀样"、"厚花环状"或"括弧样"异常信号,T1 FLAIR序列呈低信号,T2W序列呈高信号,T2 FLAIR序列呈高信号,DWI序列呈稍高或高信号,增强扫描无强化。其中3例患者经临床激素、神经营养及对症处理后复查MR,1例病灶趋于坏死,1例基本无变化,1例多次MR复查示病灶逐渐缩小;DWI序列信号均有不同程度降低。结论 MR可作为CPM的首选检查方法,其中T2 FLAIR序列为显示CPM病灶的最佳序列,DWI序列对早期病变具有重要诊断价值。 |
| 英文摘要: |
| Objective To assess the value of MRI in the diagnosis of central pontine myelinolysis (CPM) after liver transplantation. Methods Seven patients of CPM confirmed with clinic and MRI following-up after liver transplantation, and MRI features were retrospectively evaluated. Results MRI showed patchy, bat wing-like or thick chaplet abnormal signal located at mediopontine part in 7 patients. The lesions present as slightly low signal intensity on T1 FLAIR, high signal intensity on T2W and T2 FLAIR, high or slightly high signal on DWI, without enhancement in enhanced images. After glucocorticoid, neurotrophic and symptomatic treatment, 3 cases were follow-up, revealing necrotic tendency in 1 case, gradually diminished lesion in 1 case, while no obvious change was found in another case. Signal intensity on DWI decreased to different extent in these 3 patients. Conclusion MR can be used as an optimal method to diagnose CPM. T2 FLAIR and DWI can accurately display focus of CPM, and DWI plays an important role in diagnosing early CPM. |
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