| 张莹莹,徐荣天,刘屹,王欣.BOLD MRI分析肾癌及癌旁肾组织氧合状况[J].中国医学影像技术,2012,28(4):756~759 |
| BOLD MRI分析肾癌及癌旁肾组织氧合状况 |
| BOLD MRI in the evaluation of oxygenation level in renal cell carcinoma and adjacent renal tissue |
| 投稿时间：2011-09-22 修订日期：2011-11-28 |
| DOI： |
| 中文关键词: 磁共振成像 肾肿瘤 腺癌,透明细胞 |
| 英文关键词:Magnetic resonance imaging Kidney neoplasms Adenocarcinoma, clear cell |
| 基金项目:辽宁省教育厅高等学校科研项目计划(L2010665)。 |
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| 中文摘要: |
| 目的 通过BOLD MRI分析肾透明细胞癌病灶及癌旁肾组织的氧合水平。方法 使用3.0T MR对22例肾透明细胞癌患者进行术前BOLD MR检查。将BOLD原始图像输入GE ADW 4.4工作站,应用Functool软件进行后处理,并测量病灶、癌旁肾组织、远端肾组织及对侧肾组织的皮质、髓质的表观自旋-自旋弛豫率(R2*)值。对不同部位的R2*值进行统计学分析。结果 癌旁肾皮质、远端肾皮质及对侧肾皮质R2*值显著低于髓质(P<0.01)。癌旁肾髓质与远端肾髓质及对侧肾髓质R2*值差异有统计学意义(P<0.01),但远端肾髓质与对侧肾髓质R2*值间差异无统计学意义(P>0.05)。癌旁肾皮质、远端肾皮质及对侧肾皮质R2*值差异无统计学意义(P>0.05)。肾透明细胞癌病灶与癌旁肾髓质及对侧肾髓质差异有统计学意义(P<0.05),与癌旁肾皮质、远端肾皮质及对侧肾皮质差异无统计学意义(P>0.05)。结论 BOLD MRI对于评价肾透明细胞癌病灶及癌旁肾组织的氧合水平有重要价值。 |
| 英文摘要: |
| Objective To analyze the oxygenation levels of clear cell renal cell carcinoma (CRCC) and adjacent renal tissue with BOLD MRI. Methods BOLD MR imaging was performed on 22 patients with CRCC before surgery. The original images were inputed to the workstation (GE ADW 4.4) for post-process with Functool and measurement of the apparent spin-spin relaxation rate (R2*) values in different parts, including CRCC lesions, cortex and medulla of adjacent renal tissues, distal renal tissues and contralateral renal tissues. R2* values of the above locations were analyzed statistically. Results The cortical R2* values of adjacent renal tissues, distal renal tissues, and contralateral renal tissues were lower than those of the medulla (P<0.01). The medullary R2* values between adjacent renal tissues and distal renal tissues, and between adjacent renal tissues and contralateral renal tissues were statistically different (P<0.01), but the medulla R2* values between the distal renal tissues and the contralateral renal tissues were not statistically different (P>0.05). The cortex R2* values among adjacent renal tissues, distal renal tissues and contralateral renal tissues had no statistical difference (P>0.05). The R2* values were statistical different between CRCC lesions and adjacent renal medulla, as well as between CRCC lesions and the contralateral renal medulla (P<0.05), but no statistical difference among CRCC lesions and the cortex of adjacent renal tissues, distal renal tissues, contralateral renal tissues (P>0.05). Conclusion BOLD MRI is of certain value in evaluating the oxygenation levels of CRCC and adjacent renal tissue. |
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