| 石喻,郭启勇,白若冰,马跃,启文旭.降低门静脉灌注量对肝脏MR ADC值的影响[J].中国医学影像技术,2012,28(4):722~726 |
| 降低门静脉灌注量对肝脏MR ADC值的影响 |
| Impact of portal vein perfusion decrease on MRADC value of the liver |
| 投稿时间：2011-08-12 修订日期：2011-12-20 |
| DOI： |
| 中文关键词: 肝脏 扩散磁共振成像 灌注成像 |
| 英文关键词:Liver Diffusion magnetic resonance imaging Perfusion imaging |
| 基金项目:国家自然科学基金面上项目(81071123)。 |
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| 摘要点击次数: 2738 |
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| 中文摘要: |
| 目的 探讨不同b值下门静脉灌注量降低对肝脏ADC值的影响。方法 对25名健康志愿者分别在静息状态和标准运动后(有效减少门静脉灌注量)采用相位对比法定量测量门静脉灌注量,比较b值不断递增时(b为0、250、500、750、1000 s/mm2)门静脉灌注量降低对肝右前叶、右后叶ADC值的影响。结果 门静脉灌注量在运动后均显著下降,平均下降比例为43.31%。b＝500、750、1000 s/mm2时,肝右后、右前叶运动前、后ADC值的改变均无统计学意义;b＝250 s/mm2时,肝右后、右前叶ADC值的改变均有统计学意义,此时门静脉灌注量的改变量与肝右后、右前叶ADC值的变化量无确切相关性(r=0.16,P=0.45;r=0.16,P=0.46)。结论 选择较大b值(b≥500 s/mm2)可有效减小门静脉灌注量对肝脏ADC值的影响,以获得稳定、优化的ADC值。 |
| 英文摘要: |
| Objective To assess whether hepatic ADC value are influenced by hepatic perfusion decrease under different b values. Methods Totally 25 healthy volunteers underwent DWI before and after a standard exercise (an effective method to decrease portal vein flow). Phase contrast technique was used to detect the perfusion of portal vein, and breath-hold technique was taken for DWI at b-values of 0, 250, 500 and 750 and 1000 s/mm2. Then hepatic ADC values of posterior and anterior right lobe were measured and compared at different states. Results After exercise, portal blood flow decreased significantly in all volunteers, with the mean rate of 43.31%. The ADC values of posterior and anterior right lobes in b＝500, 750, 1000 s/mm2 before and after exercise had no statistical significance, while statistical significance was found when b=250 s/mm2. The decrease of portal vein flow had no relationship with ADC values of posterior and anterior right lobes when b=250 s/mm2 (r=0.16, P=0.45; r=0.16, P=0.46). Conclusion With regard to the measurements of ADC, the effect of perfusion can be minimized with higher b values (b≥500 s/mm2) in order to obtain stable and optimized ADC value. |
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