张茂春,顾鹏.超声造影判定乳腺癌前哨淋巴结的性质[J].中国医学影像技术,2012,28(3):516~519
超声造影判定乳腺癌前哨淋巴结的性质
Contrast-enhanced ultrasonography in qualitative diagnosis of sentinel lymph nodes in patients with breast carcinoma
投稿时间:2011-07-26  修订日期:2011-10-17
DOI:
中文关键词:  超声造影  乳腺肿瘤  淋巴结  活组织检查
英文关键词:Contrast-enhanced ultrasonography  Breast neoplasms  Lymph nodes  Biospy
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作者单位E-mail
张茂春 医学影像四川省重点实验室 川北医学院附属医院超声科, 四川 南充 637000  
顾鹏 医学影像四川省重点实验室 川北医学院附属医院超声科, 四川 南充 637000 linda2621@sina.com 
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中文摘要:
      目的 探讨超声造影判定乳腺癌腋窝前哨淋巴结(SLN)性质并引导手术活检的可行性。 方法 对22例乳腺癌患者,先用二维超声成像观察腋窝SLN、并综合评分判断其性质,再于乳晕周围皮下注射造影剂SonoVue,超声观察同侧腋窝SLN造影表现,判定其性质,并用细针穿刺定位引导手术切除活检。将二维超声和CEUS结果与病检结果进行比较分析。 结果 22例患者均成功在细针穿刺定位引导下完成手术切除活检。与病理结果相比,二维超声判断SLN的敏感度为87.50%(7/8)、特异度为66.67%(10/15)、准确率为73.91%(17/23);CEUS判定SLN性质的敏感度为100%(8/8)、特异度为93.33%(14/15)、准确率为95.65%(22/23)。 结论 CEUS较二维超声能更好地预测SLN的性质,并能定位引导腋窝前哨淋巴结活检。
英文摘要:
      Objective To investigate the feasibility of detecting sentinel lymph nodes (SLN) and then guiding biopsy in patients with breast carcinoma by CEUS. Methods Characteristics and properties of SLN of 22 patients with breast carcinoma were anazlyzed with 2D ultrasonography firstly. Contrast-media SonoVue were hypodermically injected around the areola of breast, and then homonymic axillary fossa sentinel node were inspected and detected by CEUS. Surgical excision guided by ultrasonography and pathological examination of SLN were executed. Results Surgical excision guided by ultrasonography successed in all 22 cases. Taking pathological result as standards, the sensitivity, specificity, accuracy of identifying SLN with 2D ultrasonography was 87.50% (7/8), 66.67% (10/15) and 73.91% (17/23), with CEUS was and 100% (8/8), 93.33% (14/15) and 95.65% (22/23), respectively. Conclusion CEUS has a good detection rate and can locate SLN and guide biopsy in patients with breast carcinoma.
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