| 王德玲,李卉,谢传淼,刘学文,耿志君,王玲.韧带样纤维瘤的影像学表现及病理特点[J].中国医学影像技术,2012,28(1):148~151 |
| 韧带样纤维瘤的影像学表现及病理特点 |
| Imaging and pathologic characteristics of desmoid tumors |
| 投稿时间：2011-07-12 修订日期：2011-08-30 |
| DOI： |
| 中文关键词: 纤维瘤 体层摄影术,X线计算机 磁共振成像 病理学 |
| 英文关键词:Fibroma Tomography, X-ray computed Magnetic resonance imaging Pathology |
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| 中文摘要: |
| 目的 探讨韧带样纤维瘤(DT)的影像学表现及病理特征。方法 回顾性分析32例DT患者的临床特征、CT、MRI及病理表现。结果 32例DT患者共38个病灶,其中84.21%(32/38)边界不清楚,39.47%(15/38)包绕侵犯血管神经,15.79%(6/38)有骨质侵犯。对11例进行CT检查,共发现14个病灶,平扫呈稍低密度,均未见坏死及钙化,增强后呈均匀或不均匀强化,强化程度等于或稍低于邻近肌肉组织。对21例进行MR检查,共发现24个病灶,T1WI上呈等或稍低于肌肉的信号,T2WI呈高于肌肉低于脂肪信号,增强扫描呈中等或明显不均匀强化;其中87.50%(21/24)可见条状或带状T1WI及T2WI低信号,增强后未见强化。组织学上肿瘤组织内纤维母细胞和成纤维细胞呈束状、编织状排列,偶见核分裂,细胞间可见胶原组织包绕。结论 T1WI、T2WI呈条带状低信号,且增强扫描不强化是DT的特征性MRI表现。CT检查可以帮助了解病灶的侵犯范围,为鉴别诊断提供一定依据。 |
| 英文摘要: |
| Objective To investigate the imaging and pathologic characteristics of the desmoid tumors (DT). Methods Clinical fentures, CT and MRI characteristics, pathological findings of 32 patients with DT proved pathologically were analyzed retrospectively. Results A total of 38 lesions of DT were found in 32 patients. Thirty-two (32/38, 84.21%) tumors showed ill-defined margins. Neurovascular involvement was detected around 15 (15/38, 39.47%), and bone involvement in 6 (6/38, 15.79%) lesions. CT scan was performed in 11 patients, and 14 lesions were detected with CT. Plain CT showed lightly low density lesions, calcification and necrosis were not found. The tumors showed homogeneous or heterogeneous enhancement after injection of contrast agent. The degree of enhancement of DT was equal to or lower than that of the muscle. Twenty-four lesions of 21 patients were found with MRI. Lesions appeared iso- or slightly hypo-intense on T1WI and hyperintense on T2WI. After contrast agent injection, the tumors showed heterogeneous moderate or intense enhancement. The band area of low signal intensity on both T1WI and T2WI without enhancement was detected in 87.50% (21/24) of the lesions. Histologically, DTs were composed of fibroblasts and myofibroblasts that were uniformed in appearance with rare mitoses, surrounded by abundant collagen. Conclusion The band area of low signal intensity on both T1WI and T2WI without enhancement is the characteristic of desmoid tumors. CT can help in assessing the invasive extent of DT and provide some certain evidence to differential diagnosis. |
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