| 谢少伟,李凤华,李红丽,夏建国,杜晶,郭祎芬,辛玫.超声造影导向活检在常规超声检查阴性前列腺癌的应用价值[J].中国医学影像技术,2011,27(11):2299~2302 |
| 超声造影导向活检在常规超声检查阴性前列腺癌的应用价值 |
| Contrast-enhanced ultrasound with contrast-tuned imaging technologyin detection of prostate cancer in patients with negative finding by conventional ultrasound |
| 投稿时间：2011-05-30 修订日期：2011-07-14 |
| DOI： |
| 中文关键词: 前列腺肿瘤 超声检查 造影剂 活组织检查 |
| 英文关键词:Prostate neoplasms Ultrasonography Contrast media Biopsy |
| 基金项目:上海市重点学科建设项目(S30203)、上海交通大学医学院附属仁济医院横向课题(2009 RJHX-07)、上海高校选拔培养优秀青年教师科研专项基金(jdy10094)。 |
|
| 摘要点击次数: 2454 |
| 全文下载次数: 938 |
| 中文摘要: |
| 目的 评价超声造影匹配成像(CnTI)技术在靶向引导常规超声无可疑前列腺癌病灶前列腺穿刺活检中的临床应用价值。方法 对56例因血清前列腺特异性抗原(PSA)升高(≥4.00 ng/ml)而常规超声未发现明确病灶的患者在穿刺前行经直肠前列腺CnTI实时扫查。在超声引导下对患者行底、中、尖三切面10点穿刺,如相应穿刺点有可疑病灶,则直接对病灶进行活检。统计分析CnTI实时扫查图像结果与病理结果。结果 56例患者共穿刺560针,穿刺病理诊断为前列腺癌11例(11/56,19.64%)共39针(39/560,6.96%),CnTI实时扫查检出7例(7/11,63.64%)共22针(22/39,56.41%)。在4例CnTI实时扫查假阴性病例中,2例仅有1针穿刺点阳性,1例2针穿刺点阳性,1例3针穿刺点阳性,其Gleason分值均为6分。CnTI实时扫查真阳性与假阴性前列腺癌穿刺点Gleason分值差异无统计学意义(6.9 vs 6.6, P=0.134)。结论 对血清PSA升高但常规超声未发现明确前列腺癌病灶的患者,经直肠前列腺CnTI实时扫查有助于检出前列腺癌可疑病灶并指导前列腺穿刺活检。 |
| 英文摘要: |
| Objective To observe the value of contrast-enhanced ultrasound (CEUS) using contrast-tuned imaging (CnTI) technology on detection of prostate cancer in patients with negative finding by conventional ultrasound. Methods Fifty-six patients with serum prostate-specific antigen levels ≥4.00 ng/ml but no foci found by conventional ultrasound were evaluated with CnTI examinations and then sonographically guided biopsy. Biopsy was performed at 10 sites of the base, the mid gland and the apex in each patient. When CnTI scanning showed abnormality, the biopsy specimen from the corresponding site was directed toward the abnormal finding. The performances of CnTI for prostate cancer detection were analyzed based on biopsy results. Results The overall prostate cancers were detected in 39 (39/560, 6.96%) of 560 sites and 11 (11/56, 19.64%) of 56 patients. Twenty-two sites (22/39, 56.41%) from 7 (7/11, 63.64%) patients were detected by CnTI. Of the 4 patients with a Gleason score of 6 in whom prostate cancer was not detected by CnTI, 2 patients had only one positive site, 1 patient had two positive sites, 1 patient had three positive sites. The mean Gleason score of cancers with CnTI positive findings and negative findings was not significantly different (6.9 vs 6.6, P=0.134). Conclusion CEUS using CnTI technology can be used to find the suspicious areas of prostate cancer and direct biopsy in patients with increased PSA level but no significant foci on conventional ultrasonography. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
