| 刘恩涛,王淑侠,谢淑飞,邵丹.胰岛素瘤动态三期增强CT和18F-FDG PET/CT影像分析[J].中国医学影像技术,2011,27(11):2261~2264 |
| 胰岛素瘤动态三期增强CT和18F-FDG PET/CT影像分析 |
| Triple-phase contrast-enhanced multi-spiral |
| 投稿时间：2011-05-10 修订日期：2011-07-15 |
| DOI： |
| 中文关键词: 胰岛素瘤 体层摄影术,X线计算机 正电子发射型体层摄影术 18F 氟脱氧葡萄糖 |
| 英文关键词:Insulinoma Tomography, X-ray computed Positron-emission tomography Fluorodeoxyglucose F18 |
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| 中文摘要: |
| 目的 探讨胰岛素瘤MSCT动态三期增强及18F-FDG PET/CT显像的影像学特点。方法 回顾性分析我院6例经手术病理证实的胰岛素瘤的临床资料和18F-FDG PET/CT及同机MSCT动态三期增强影像资料。结果 6例患者均有不同程度低血糖发作病史和典型的惠普尔三联征,其中2例以精神症状首诊。全部病例空腹或发作时血糖均<2.8 mmol/L,胰岛素释放指数均>0.3。6例胰岛素瘤均为单发,1例位于胰尾,2例位于胰体,3例位于胰头,肿瘤直径0.8 cm×0.9 cm~3.0 cm×3.8 cm,平均1.6 cm×1.6 cm。CT平扫肿瘤呈均匀等或稍低密度,边界不清;增强扫描动脉期呈明显均匀强化,静脉期及延迟期强化程度逐渐减低,动脉期强化最为显著。6例患者中,5例肿瘤局部18F-FDG摄取未见增高,1例多发性内分泌肿瘤1型(MEN 1)相关胰岛素瘤局部18F-FDG摄取增高,SUVmax＝4.8。结论 MSCT动态三期增强扫描可清晰显示肿瘤的形态和位置,18F-FDG PET/CT对本病诊断价值有限。 |
| 英文摘要: |
| Objective To observe triple-phase contrast-enhanced multi-spiral CT (MSCT) and 18F-FDG PET/CT imaging features of insulinoma. Methods Clinical data and image data (whole body 18F-FDG PET/CT and triple-phase contrast-enhanced MSCT in the same unit) of 6 patients with insulinoma confirmed by postoperative pathology were analyzed retrospectively. Results All patients had history of hypoglycemia attack and typical Whipple triad, and two of them complained of mental symptoms at the first visit. The fasting blood glucose or blood glucose concentration in clinical attack time of all the cases were lower than 2.8 mmol/L. The insulin release index was greater than 0.3 in all patients. The tumor in all patients was single, located in pancreatic head in 3 cases, pancreatic body in 2 cases, pancreatic tail in 1 case. The mean size of the tumor was 1.6 cm×1.6 cm (0.8 cm×0.9 cm-3.0 cm×3.8 cm). The tumor presented as ill-defined lesion, with homogeneous slightly low density on plain CT. During the hepatic arterial phase, the tumor exhibited homogeneous intense enhancement. During the period of portal vein and delayed scan, the enhancement of the tumor decreased. Among 6 cases, only 1 case with multiple endocrine neoplasia type 1 (MEN 1)-related insulinoma proved positive on PET, and the SUVmax was 4.8. Conclusion Dynamic triple-phase contrast-enhanced MSCT can clearly display the shape and location of insulinoma, while the diagnostic value of 18F-FDG PET/CT for insulinoma was limited. |
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