白志勇,李敬府,杨玉杰,张华斌,刘蕾,李小刚,贾建文.颈动脉斑块超声造影增强特征与脑梗死的关系[J].中国医学影像技术,2011,27(11):2194~2197
颈动脉斑块超声造影增强特征与脑梗死的关系
Relationship between contrast enhanced ultrasound imaging of carotid plaques and brain infarction
投稿时间:2011-04-16  修订日期:2011-07-09
DOI:
中文关键词:  超声检查  造影剂  颈动脉  粥样硬化  脑梗死
英文关键词:Ultrasonography  Contrast media  Carotid  Atherosclerosis  Brain infarction
基金项目:教育部留学回国人员科研启动基金(19-850-600)。
作者单位E-mail
白志勇 北京大学第三医院超声诊断科,北京 100191  
李敬府 北京大学第三医院超声诊断科,北京 100191 jfli_pku@163.com 
杨玉杰 北京大学第三医院超声诊断科,北京 100191  
张华斌 北京大学第三医院超声诊断科,北京 100191  
刘蕾 北京大学第三医院神经内科,北京 100191  
李小刚 北京大学第三医院神经内科,北京 100191  
贾建文 北京大学第三医院超声诊断科,北京 100191  
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中文摘要:
      目的 探讨颈动脉斑块CEUS增强特征与脑梗死之间的关系。方法 以彩色多普勒超声观察136例患者有无颈动脉斑块。将颈动脉斑块CEUS增强特征分为3级:无增强(1级)、基底部增强(2级)和中心部增强(3级)。比较脑梗死和无脑梗死患者颈动脉斑块CEUS增强特征,随访观察各级增强颈动脉斑块患者中的新发脑梗死病例比例。结果 近期脑梗死同侧颈动脉斑块出现2级、3级增强者分别占30.77%(16/52)和40.38%(21/52),陈旧性脑梗死为28.00%(21/75)和21.33%(16/75),无脑梗死患者为24.03%(31/129)和8.53%(11/129),三者比较差异有统计学意义(χ2=31.56,P<0.01)。随访发现,1、2、3级增强斑块,同侧大脑半球新发脑梗死比例分别为1.47%(2/136)、8.93%(5/56)和7.14%(3/42),差异有统计学意义(P<0.05)。结论 颈动脉斑块CEUS增强特征与脑梗死关系密切。
英文摘要:
      Objective To investigate the correlation of carotid plaques characteristics detected by contrast enhanced ultrasound (CEUS) with brain infarction. Methods Carotid atherosclerosis plaques of 136 patients were imaged with CEUS. Contrast enhancement within plaques were categorized as absent (grade 1), peripheral (grade 2) and extensive internal (grade 3). The patients were followed up for stroke occurrence. Results Recent brain infarction patients had higher degree of plaques enhancement which were 30.77% (16/52) in grade 2 and 40.38% (21/52) in grade 3, while old brain infarction had 28.00% (21/75) in grade 2 and 21.33% (16/75) in grade 3, respectively, and patients without brain infarction had 24.03% (31/129) in grade 2 and 8.53% (11/129) in grade 3 (χ2=31.56, P<0.01). Stroke occurrence ratio was 8.93% (5/56) in patients with grade 2 enhancement plaques and 7.14% (3/42) in patients with grade 3 enhancement plaques, both higher than that of patients with no plaques enhancement (2/136, 1.47%, P<0.05). Conclusion Carotid plaques contrast enhancement have significant correlation with brain infarction.
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