| 葛群,张伟娟,李东至.超声检测水肿胎儿静脉导管血流频谱的变化[J].中国医学影像技术,2011,27(9):1895~1898 |
| 超声检测水肿胎儿静脉导管血流频谱的变化 |
| Evaluation on changes of ductus venosus in hydrops fetalis with Doppler ultrasonography |
| 投稿时间：2011-04-09 修订日期：2011-06-09 |
| DOI： |
| 中文关键词: 胎儿水肿 超声检查,多普勒 静脉导管 α-地中海贫血 心脏病 |
| 英文关键词:Hydrops fetalis Ultrasonography, Doppler Ductus venosus alpha-Thalassemia Heart diseases |
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| 中文摘要: |
| 目的 分析水肿胎儿的静脉导管(DV)血流参数,观察心源性水肿及重型α-地中海贫血引起的胎儿水肿者DV血流频谱改变。 方法 选取产前超声检查发现的69胎水肿胎儿,根据病因分心源性水肿组(17胎)和重型α-地中海贫血组(52胎),分别测量DV血流频谱并进行参数分析。 结果 心源性水肿组88.24%(15/17)DV出现心室收缩期峰值速度(S)波降低、心房收缩期峰值速度(a)波缺失或反向,静脉峰值流速指数(PVIV)、DV搏动指数(DVPI)及DV阻力指数(DVRI)升高。重型a-地中海贫血组50.00%(26/52)表现为S波增高,59.62%(31/52)a波增高,69.23%(36/52)PVIV减低,80.77%(42/52)DVRI降低,86.53%(45/52)DVPI降低。两组比较,水肿胎儿DV血流频谱与相应孕周正常胎儿DV参考值的差值差异有统计学意义(P<0.01)。 结论 两组水肿胎儿DV血流频谱改变不同。DV血流参数对于鉴别胎儿水肿病因及指导临床诊疗有重要意义。 |
| 英文摘要: |
| Objective To investigate the different changes of ductus venosus (DV) parameters of hydrops fetalis, including fetuses with homozygous α-thalassemia and fetuses with heart disease. Methods Sixty-nine hydropic fetuses were recruited and divided into cardiogenic group (n=17) and homozygous α-thalassemia group (n=52). Fetal DV blood flow was measured. Results In cardiogenic group, 88.24% (15/17) had low velocity of peak forward velocity during systole (S), high peak velocity index in veins (PVIV), high DV pulse index (DVPI), high DV resistance index (DVRI) and absent or reversed lowest forward velocity (a). In homozygous α-thalassemia group, 50.00% (26/52) had high velocity of S wave, 59.62% (31/52) had high velocity of a wave, 69.23% (36/52) had low PVIV, 80.77% (42/52) had low DVRI and 86.53% (45/52) had low DVPI. There were significant differences between the two groups (P<0.01). Conclusion Changes of DV Doppler were different between hydrops fetalis caused by homozygous α-thalassemia or heart disease. Checking and measure DV parameters are important to distinguish the causes of hydrop fetalis and clinical management. |
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