刘记存,陈勇,崔建岭.SAPHO综合征的影像表现[J].中国医学影像技术,2011,27(8):1684~1687
SAPHO综合征的影像表现
Imaging features of SAPHO syndrome
  
DOI:
中文关键词:  SAPHO综合征  诊断,鉴别  放射摄影术  体层摄影术,X线计算机  磁共振成像
英文关键词:SAPHO syndrome  Diagnosis, differential  Radiography  Tomography, X-ray computed  Magnetic resonance imaging
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作者单位E-mail
刘记存 河北医科大学第三医院放射科,河北 石家庄 050051 ljcqsy@163.com 
陈勇 河北医科大学第三医院放射科,河北 石家庄 050051  
崔建岭 河北医科大学第三医院放射科,河北 石家庄 050051  
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中文摘要:
       目的 探讨SAPHO综合征的影像学表现。方法 回顾性分析20例SAPHO综合征患者的影像学表现。结果 19例病变累及前上胸壁,X线、CT表现为骨及肋软骨硬化、肥厚,关节破坏、强直,胸骨柄、锁骨近端和第1肋软骨受累,其中双侧不对称受累8例,双侧对称性受累7例,单侧受累4例。10例柄胸联合受累,6例第2肋软骨受累。5例伴有脊柱病变,X线、CT表现为多发椎体终板侵蚀、硬化,椎旁骨化,椎间隙变窄,椎体楔形变;MRI表现为椎体不均匀长T1长T2信号。3例伴骶髂关节受累,X线和CT表现为关节破坏、强直。结论 前上胸壁病变是SAPHO综合征最具特征性的影像学表现。
英文摘要:
      Objective To explore the imaging features of patients with synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome. Methods Imaging features of 20 patients with SAPHO syndrome were retrospectively analyzed. Results Nineteen patients had anterior chest wall involvement, which showed bone sclerosis, hyperostosis, costal cartilage sclerotic hyperostosis, joint destruction and ankylosis on plain X-ray films and CT images. The medial end of clavicle, manubrium and the first costal cartilage were affected in 19 cases. Among them, bilaterally asymmetrical involvements were found in 8 cases, bilaterally symmetrical in 7 cases and unilateral in 4 cases, respectively. Manubriosternal junctions and the second costal cartilages were affected in 10 and 6 cases, respectively. Five patients had spinal involvement which showed endplate erosion, sclerosis, paravertebral ossification, narrowed disc space, wedged body on plain film and CT, inhomogeneous long T1 and long T2 signal intensities on MRI. Three patients also had sacroiliac joint involvement which showed joint destruction and ankylosis on plain film and CT. Conclusion Anterior chest wall lesions are the typical imaging features of SAPHO syndrome.
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