| 崔斌,赵长伶,贺建新,张晓锦.全胰腺CT灌注成像在2型糖尿病患者中的应用[J].中国医学影像技术,2011,27(8):1629~1632 |
| 全胰腺CT灌注成像在2型糖尿病患者中的应用 |
| Whole-organ CT perfusion imaging of the pancreas in patients with type 2 diabetes |
| |
| DOI： |
| 中文关键词: 体层摄影术,X线计算机 灌注成像 糖尿病,2型 胰腺 |
| 英文关键词:Tomography, X-ray computer Perfusion imaging Diabetes mellitus, type 2 Pancreas |
| 基金项目: |
|
| 摘要点击次数: 3670 |
| 全文下载次数: 1230 |
| 中文摘要: |
| 目的 应用64排容积CT全胰腺灌注扫描成像技术定量分析不同患病时间2型糖尿病患者胰腺灌注参数,初步探讨其在反映糖尿病患者胰腺微循环中的作用。方法 将54例2型糖尿病患者按照患病时间分为3组, A组13例,病程1~5年,B组16例,病程6~10年,C组25例,病程＞10年,行64排容积CT全胰腺灌注检查,测量胰腺头、颈、体和尾部实质的径线和灌注参数,包括血流量(BF)、血流容积(BV)、平均通过时间(MTT)、达峰时间(TTP)、表面通透性(PS)并进行统计学分析。结果 ①各组内胰腺不同部位(头、颈、体和尾部)比较,灌注参数(BV、BF、MTT、PS和TTP)差异无统计学意义(P均>0.05)。②A组与B、C组比较,胰腺头、体部MTT差异有统计学意义(P均<0.05);A组与B组比较,胰腺颈部MTT、BF及PS差异有统计学意义(P均<0.05)。③A组与C组比较,胰腺体、尾部径线差异有统计学意义(P均<0.05),B组与C组比较,胰腺尾部径线差异有统计学意义(P<0.05)。结论 全胰腺CT灌注成像对评价2型糖尿病患者胰腺微循环情况有一定价值。 |
| 英文摘要: |
| Objective To quantitatively analyze the whole-organ perfusion parameters of pancreas using 64-slice volume CT according to disease duration, and to observe the value of perfusion technology in pancreatic microcirculations in patients with type 2 diabetes. Methods Totally 54 patients with type 2 diabetes were divided into 3 groups according to disease duration, i.e. Group A, 13 patients with duration 1—5 years, Group B, 16 patients with duration 6—10 years, and Group C, 25 patients with duration longer than10 years, and all the patients underwent pancreatic CT perfusion imaging. The mean blood flow (BF), blood volume (BV), mean transit time (MTT), time to peak (TTP), permeability surface area product (PS) and the size in each location (head, neck, body and tail) were measured and statistically analyzed. Results ①The perfusion parameters of patients in the same group showed no statistical difference among different locations of pancreas (all P>0.05). ②There were statistical differences between Group A and B, Group A and C in MTT at the head and body of pancreas (all P<0.05). Statistical differences were noted between Group A and B in BF, MTT and PS at the neck of pancreas (all P<0.05). ③There were statistical differences of sizes of pancreatic body and tail between Group A and C (all P<0.05), as well as sizes of tail of pancreas between Group B and C (all P<0.05). Conclusion Whole-organ CT perfusion parameters of pancreas conduce to the evaluation of pancreatic microcirculatory changes in patients with type 2 diabetes. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
