| 秦乃姗,王丹丹,王霄英.乳腺密度与年龄、月经状态及乳腺癌的相关性[J].中国医学影像技术,2011,27(8):1607~1609 |
| 乳腺密度与年龄、月经状态及乳腺癌的相关性 |
| Correlation between mammographic density and age, menopausal status and risk of breast cancer |
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| DOI： |
| 中文关键词: 乳腺密度 乳腺肿瘤 年龄因素 月经状态 |
| 英文关键词:Breast density Breast neoplasms Age factors Menopausal status |
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| 中文摘要: |
| 目的 探讨乳腺密度与女性年龄、月经状态及乳腺癌之间的相关性。方法 收集我院2009年6月—2010年7月数字乳腺X线摄影检查资料,包括确诊乳腺癌患者79例(乳腺癌组)和健康体检人群481名(对照组)。DR原始图像经R2工作站Quantra软件处理,计算机自动计算出乳腺密度。比较对照组双侧乳腺密度差异;对照组乳腺密度与年龄及月经状态是否具有相关性。比较乳腺癌组与对照组的乳腺密度差异。结果 对照组双侧乳腺密度 差异无统计学意义。乳腺密度与年龄具有相关性(P＜0.001),随年龄增长乳腺密度降低;绝经人群的乳腺密度 显著低于未绝经人群 。50岁以下的平均乳腺密度在乳腺癌组高于对照组,但两者差异无统计学意义。结论 乳腺密度随着年龄增长而逐渐减低,绝经女性乳腺密度低于未绝经女性。 |
| 英文摘要: |
| Objective To explore the relationship between mammographic density and age, menopausal status and risk of breast cancer. Methods Data of digital mammography in 79 patients with confirmed breast cancer (breast cancer group) and 481 control subjects (control group) from Jun 2009 to Jul 2010 were collected. The breast density was computed automatically using R2 workstation Quantra software on digital mammograms. In control group, the mammographic density of left breasts was compared with that of the right ones, the associations between mammographic density and age, menopausal status were tested. And differences of density between breast cancer group and control group were compared. Results There was no significant difference between bilateral breasts in control group (right, %; left, %). As age increasing, the mammographic density decreased. The mammographic density in postmenopausal women ( %) was significant lower than that in premenopausal women ( %, P＜0.001). For women under 50 years old, the density in breast cancer group was higher than that in control group, but no significant difference was found. Conclusion Breast density decreases with age, and is lower in menopause women than that in premenopausal ones. |
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