| 宗会迁,刘怀军,宋鹏,柳青,付凯亮.MR扩散张量成像诊断慢性脊髓型颈椎病[J].中国医学影像技术,2011,27(8):1555~1558 |
| MR扩散张量成像诊断慢性脊髓型颈椎病 |
| MR diffusion tensor imaging in diagnosis of chronic cervical spondylotic myelopathy |
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| DOI： |
| 中文关键词: 慢性脊髓型颈椎病 扩散磁共振成像 |
| 英文关键词:Chronic cervical spondylotic myelopathy Diffusion magnetic resonance imaging |
| 基金项目:河北省自然科学基金(C2008001109)。 |
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| 中文摘要: |
| 目的 探讨3.0T MR DTI诊断慢性脊髓型颈椎病的价值。 方法 应用SE-EPI序列对64例病程超过2年的慢性脊髓型颈椎病患者(CSM组)和31名健康志愿者(对照组)行颈髓DTI。将颈髓分为上、中、下三段,分析CSM组各段颈髓ADC值、FA值、纵向本征(λL)值及横向本征(λT)值的变化。结果 所有受检者颈髓DTI显示满意。CSM组上、中、下各段颈髓的ADC值(F＝251.20)、FA值(F＝47.54)、λL值(F＝210.14)、λT值(F＝104.39)差异均有统计学意义(P均＜0.0001)。对照组上、中、下各段颈髓的平均ADC值为(0.81±0.06)×10-3 mm2/s,FA值为0.65±0.04,λL值为(1.66±0.10)×10-3 mm2/s,λT值为(0.47±0.04)×10-3 mm2/s,在颈髓各节段之间各参数值差异无统计学意义。与对照组比较,CSM组直接受压部位处ADC、FA、λL、λT的t值分别为20.84、12.53、6.00和20.84,差异有统计学意义(P均＜0.05)。 结论 通过ADC、FA、λL和λT能够检测颈髓微观结构的变化。DTI是判定慢性脊髓型颈椎病脊髓受压范围和受损程度的有效方法。 |
| 英文摘要: |
| Objective To observe the value of DTI in diagnosis of chronic cervical spondylotic myelopathy with 3.0T MR. Methods DTI were performed in 64 patients with chronic cervical spondylotic myelopathy exceeded two years (CSM group) and 31 consecutive healthy subjects (control group) using SE-EPI sequence on the cervical spinal cord. The cervical cord was divided into the upper cervical cord, the mid cervical cord and the lower cervical cord according to anatomic structures.ADC, FA, longitudinal eigenvalue (λL) and horizontal eigenvalue (λT) of every segment cervical cord were measures and analyzed. Results High quality ADC maps and FA maps were obtained in all subjects. In CSM group, significant differences of ADC (F＝251.20), FA (F＝47.54), λL (F＝210.14) and λT (F＝104.39) values were found among 3 cervical cord regions (all P＜0.0001). In control group, the average ADC, FA, λL and λT values were (0.81±0.06)×10-3 mm2/s, 0.65±0.04, (1.66±0.10)×10-3 mm2/s and (0.47±0.04)×10-3 mm2/s, respectively, no significant difference was found among 3 cervical cord regions. There were significant differences of ADC (t=20.84), FA (t=12.53), λL (t=6.00) and λT (t=20.84) values between CSM group and the control group (P＜0.05). Conclusion ADC, FA, λL and λT values are sensitive to observe changes of cervical spinal cord. DTI is useful to reflect the sites and severity of cord injury in chronic cervical spondylosis patients. |
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