| 戚庭月,陈亚青,苗华栋,朱云开,蒋珺,姚晓虹.经DWI定位经直肠超声引导下前列腺穿刺活检术诊断前列腺癌[J].中国医学影像技术,2011,27(7):1485~1489 |
| 经DWI定位经直肠超声引导下前列腺穿刺活检术诊断前列腺癌 |
| Diffusion weighted imaging for locating of prostate cancer before transrectal ultrasound-guided transperineal prostate biopsy |
| 投稿时间：2010-12-18 修订日期：2011-03-04 |
| DOI： |
| 中文关键词: 前列腺肿瘤 扩散磁共振成像 超声检查,经直肠 活组织检查 |
| 英文关键词:Prostatic neoplasms Diffusion magnetic resonance imaging Ultrasonography, transrectal Biopsy |
| 基金项目:上海市科委基础研究重点项目(10JC1411400)、上海市科委临床研究重点项目(10411952000)、上海市科学技术委员会基金(09411963800)。 |
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| 中文摘要: |
| 目的 探讨经DWI定位经直肠超声(TRUS)引导下目标穿刺方法诊断前列腺癌(PCa)的价值。方法 对50例临床疑似PCa患者行DWI,之后于TRUS引导下行经会阴前列腺穿刺术。采用系统穿刺(SB)与DWI目标穿刺(DWI-TB)相结合进行穿刺。根据穿刺病理结果,分别统计DWI-TB、SB及DWI-TB+SB的PCa检出率和穿刺阳性率。结果 DWI-TB和SB及DWI-TB+SB对PCa的检出率分别为54.00%(27/50)、46.00%(23/50)和66.00%(33/50),其中DWI-TB+SB与单纯SB相比差异有统计学意义(P<0.05);DWI-TB、SB及DWI-TB+SB穿刺阳性率分别为40.41%(59/146)、9.33%(39/418)和14.23%(72/506),三种穿刺方案穿刺阳性率差异有统计学意义(P<0.05)。结论 DWI有助于发现可疑PCa病灶,为TRUS引导下经会阴前列腺穿刺提供目标、特别是移行区目标信息,联合运用SB和DWI-TB价值较高。 |
| 英文摘要: |
| Objective To observe the value of DWI for predicting location of prostate cancer before transrectal ultrasound (TRUS)-guided transperineal prostate biopsy. Methods A total of 50 patients with suspected prostate cancer underwent DWI before TRUS-guided biopsy of the prostate. The biopsies were carried out using 8 core systematic biopsy (SB) and (or) DWI-targeted biopsy (DWI-TB). According to histopathology results, the prostate cancer detection rate and the positive rate of punctures of DWI-TB, SB and DWI-TB+SB were evaluated. Results The prostate cancer detection rate of DWI-TB, SB and DWI-TB+SB was 54.00% (27/50), 46.00% (23/50) and 66.00% (33/50), respectively. There was significant difference of the detection rate of prostate cancer between DWI-TB+SB and SB (P<0.05). The positive rate of puncture with DWI-TB, SB and DWI-TB+SB was 40.41% (59/146), 9.33% (39/418) and 14.23% (72/506), respectively. There were significant differences of the positive rates of puncture among all three methods (P<0.05). Conclusion DWI may predict the location of prostate cancer and provide information of the target especially in the transition zone for the TRUS-guided transperineal prostate biopsy. The diagnostic accuracy of prostate cancer increases with combined application of DWI-TB and SB. |
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