| 徐方元,陈爽,关颖,叶春梅,秦少华,徐瑛,王建民,陈晓荣,韩云学,叶春燕.多层螺旋CT脑灌注成像与血管成像联合评价颈动脉狭窄性短暂性脑缺血发作[J].中国医学影像技术,2011,27(7):1370~1373 |
| 多层螺旋CT脑灌注成像与血管成像联合评价颈动脉狭窄性短暂性脑缺血发作 |
| Combination of cerebral CT perfusion and CT angiography in evaluation of internal carotid artery stenosis in patients with transient ischemic attacks |
| 投稿时间：2011-01-25 修订日期：2011-03-29 |
| DOI： |
| 中文关键词: 颈动脉狭窄 脑缺血发作,短暂性的 灌注成像 血管造影术 |
| 英文关键词:Carotid stenosis Ischemic attack, transient Perfusion imaging Angiography |
| 基金项目:上海市宝山区科委科技发展基金(09-E-25)。 |
| 作者 | 单位 | E-mail | | 徐方元 | 复旦大学附属华山医院宝山分院放射科,上海 200431 | fangyuan.tsu@gmail.com | | 陈爽 | 复旦大学附属华山医院放射科,上海 200040 | | | 关颖 | 复旦大学附属华山医院宝山分院神经内科,上海 200431 | | | 叶春梅 | 复旦大学附属华山医院宝山分院放射科,上海 200431 | | | 秦少华 | 复旦大学附属华山医院宝山分院放射科,上海 200431 | | | 徐瑛 | 复旦大学附属华山医院宝山分院神经内科,上海 200431 | | | 王建民 | 复旦大学附属华山医院宝山分院神经内科,上海 200431 | | | 陈晓荣 | 复旦大学附属华山医院宝山分院放射科,上海 200431 | | | 韩云学 | 复旦大学附属华山医院宝山分院放射科,上海 200431 | | | 叶春燕 | 复旦大学附属华山医院宝山分院放射科,上海 200431 | |
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| 中文摘要: |
| 目的 探讨多层螺旋CT脑灌注成像(CTP)与CTA联合评价颈动脉狭窄性短暂性脑缺血发作(TIA)的价值。 方法 对26例临床诊断TIA患者行头颅CT平扫、脑CTP和颈动脉CTA。评价脑CTP的达峰时间(TTP)、脑血流量(CBF)、脑血容量(CBV)以及颈动脉的狭窄程度及斑块的性质。选取20名无TIA病史的志愿者作为对照。 结果 26例中,21例头颅CT平扫正常,5例有腔隙性脑梗死。脑CTP检查正常9例,异常17例,患者患侧与对侧的TTP、CBF差异有统计学意义(P<0.01)。CTA显示颈动脉狭窄19例,发现颈动脉斑块44处。随访6个月中3例发生脑梗死。 结论 脑CTP结合CTA对评价TIA具有较高的临床应用价值。 |
| 英文摘要: |
| Objective To observe the value of MSCT cerebral perfusion imaging combined with CTA in assessment of transient ischemic attacks (TIA) resulted from internal carotid artery occlusive diseases. Methods Conventional CT, CTA and CT perfusion imaging (CTP) were performed in 26 patients with clinically diagnosed TIA. The time to peak (TTP), cerebral blood flow (CBF) and cerebral blood volume (CBV) were evaluated. The stenosis of carotid arteries was assessed. And 26 normal volunteers were enrolled as control. Results In 26 patients with TIA, plain CT showed lacunar infarctions only in 5 patients. CTP showed abnormal in 17 patients, among them TTP and CBF of the stenotic side were significantly different compared with those of the contralateral side (P<0.01). Nineteen stenosis internal carotid arteries and 44 carotid artery plaques were found with CTA. Cerebral infarction happened on 3 patients within 6 months. Conclusion CTP combined with CTA can provide valuable diagnostic information for patients with TIA. |
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