郑加贺,刘兆玉,卢再鸣,畅智慧,赵健,郭启勇.药物洗脱支架在膝下动脉病变的初步应用[J].中国医学影像技术,2011,27(3):545~547 |
药物洗脱支架在膝下动脉病变的初步应用 |
Initial experiences of drug eluting stents in infrapopliteal artery |
投稿时间:2010-11-17 修订日期:2010-12-06 |
DOI: |
中文关键词: 药物洗脱支架 膝下动脉 血管成形术 |
英文关键词:Drug-eluting stents Infrapopliteal artery Angioplasty |
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中文摘要: |
目的 探讨药物洗脱支架在膝下动脉应用的可行性及临床价值。方法 对11例接受Deep球囊扩张术后效果不满意的膝下动脉病变患者植入国产药物洗脱支架,观察术后临床症状改善情况,比较术前及术后的踝肱指数,应用超声随访支架的再狭窄情况。结果 患者术后缺血症状均明显改善,踝肱指数为0.84±0.09,较术前(0.35±0.12)明显增高(P<0.05)。术后6个月, 11例患者膝下动脉支架均血流通畅,未见狭窄;术后随访12个月的8例患者中,2例支架近端轻度狭窄(直径减少小于30%)。结论 药物洗脱支架用于治疗膝下动脉病变的近期疗效肯定,中远期效果有待进一步观察。 |
英文摘要: |
Objective To investigate the feasibility and clinical value of drug eluting stents (DES) in infrapopliteal artery. Methods Domestic-made DES was used in infrapopliteal artery of 11 patients with unsatisfactory results after percutaneous transluminal angioplasty (PTA) with Deep balloon. After the procedure, the improvement of clinical symptoms was observed. The ankle/brachial index (ABI) of post-treatment was compared with that of pre-treatment and in-stent restenosis was followed with ultrasound. Results The limb ischemic symptoms were improved markedly after therapy. The ABI was 0.84±0.09 for post-treatment and 0.35±0.12 for pre-treatment, respectively (P<0.05). In the stents of infrapopliteal arteries, no restenosis was found after following for 6 months, while mild stenosis (diameter reduction <30%) at proximal end was found with 2 of 8 patients after following for 12 months. Conclusion The DES implantation in infrapopliteal artery is efficient in the near future, and further study is needed for the long-term results. |
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