姜小力,邓学东,李晓兵.胎儿胼胝体发育不良的超声和磁共振对比观察[J].中国医学影像技术,2011,27(2):357~360
胎儿胼胝体发育不良的超声和磁共振对比观察
Comparison of ultrasound and MRI in the prenatal diagnosis of agenesis of corpus callosum
投稿时间:2010-09-13  修订日期:2010-11-02
DOI:
中文关键词:  超声检查,产前  磁共振成像  胼胝体  畸形  胎儿
英文关键词:Ultrasonography, prenatal  Magnetic resonance imaging  Corpus callosum  Abnormalities  Fetus
基金项目:
作者单位E-mail
姜小力 南京医科大学附属苏州医院 苏州市立医院本部超声中心,江苏 苏州 215002  
邓学东 南京医科大学附属苏州医院 苏州市立医院本部超声中心,江苏 苏州 215002 xuedongdeng@163.com 
李晓兵 南京医科大学附属苏州医院 苏州市立医院本部超声中心,江苏 苏州 215002  
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中文摘要:
      目的 探讨超声与MRI在胎儿胼胝体发育不良(ACC)产前诊断中的应用价值。方法 超声怀疑胎儿ACC孕妇16名,均在超声检查后3天内接受胎儿MR检查。将超声、MRI结果与出生后或引产后结果对照。结果 16名孕妇共检出胎儿16胎,MRI证实14胎为胎儿ACC(出生后随访证实5胎,引产后证实9胎),1胎为单纯双侧脑室扩张伴灰质易位,1胎为脑白质、脑干发育不良。MRI与超声比较,诊断胎儿ACC一致者7胎;超声可疑、MRI肯定者7胎;对于其伴发中枢神经系统畸形,两者一致者7胎,MRI多于超声者4胎。结论 超声检查是产前筛查胎儿ACC的普遍方法;MRI对胎儿ACC的显示明显优于超声,有助于明确诊断胎儿ACC并判断其分型及合并畸形。
英文摘要:
      Objective To observe the value of ultrasound (US) and MRI in the prenatal diagnosis of agenesis of corpus callosum (ACC). Methods Fetal ACC was suspected in 16 pregnant women by prenatal US. Fetal MRI was performed within 3 days after prenatal US. The findings of prenatal US and fetal MRI were compared with the results of autopsy or following up imaging data after birth. Results Sixteen fetuses were detected in 16 pregnant women. Fourteen fetuses of ACC suspected with prenatal US were confirmed with MRI (5 confirmed with following-up after birth and 9 with autopsy). Another 2 fetuses were not ACC, 1 was ventriculomegaly companying with gray matter translocation and the other was cerebral white matter and brain stem hypoplasia. Of all the fetal ACC confirmed with MRI, US was consistent with MRI in 7 fetuses, and other 7 fetuses were suspected with US. For the other associated abnormalities in central nervous system, MRI was consistent with prenatal US in 7 fetuses. MRI demonstrated more associated abnormalities than US in 4 fetuses. Conclusion US is the optimal choice for detecting fetal anomalies. However, MRI is superior to US in the diagnosis of ACC and contributes to the definite diagnosis of ACC and possible associated abnormalities.
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