龚静山,刘特,陈杰,朱进,徐坚民.多层CT虚拟胃镜显示胃癌:与光学胃镜和病理结果对照[J].中国医学影像技术,2011,27(2):345~348
多层CT虚拟胃镜显示胃癌:与光学胃镜和病理结果对照
Multi-slice CT virtual gastroscopy in demonstrating gastric cancer: Comparison with optical gastroscopy and pathology
投稿时间:2010-10-11  修订日期:2010-11-07
DOI:
中文关键词:  胃肿瘤  胃镜检查  体层摄影术,X线计算机
英文关键词:Stomach neoplasms  Gastroscopy  Tomography, X-ray computed
基金项目:深圳市科技计划项目(医疗卫生类)(200902001)。
作者单位E-mail
龚静山 深圳市人民医院 暨南大学第二临床医学院放射科,广东 深圳 518020 jshgong@sina.com 
刘特 深圳市人民医院 暨南大学第二临床医学院放射科,广东 深圳 518020  
陈杰 深圳市人民医院 暨南大学第二临床医学院放射科,广东 深圳 518020  
朱进 深圳市人民医院 暨南大学第二临床医学院放射科,广东 深圳 518020  
徐坚民 深圳市人民医院 暨南大学第二临床医学院放射科,广东 深圳 518020  
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中文摘要:
      目的 探讨多层CT虚拟胃镜(VG)与轴位图像对胃癌检出的价值,并与光学胃镜和病理对照。方法 对连续67例经光学胃镜活检证实或高度怀疑胃癌的患者,在服产气粉充分扩张胃后行多层螺旋CT薄层扫描后行VG。由2名放射诊断医师在不知光学胃镜结果的情况下分别评估VG和CT轴位图像,并通过协商达成一致。评价结果与光学胃镜和手术切除大体标本比较,采用McNemar检验比较VG图像和CT平扫轴位图像对胃癌灶的检出率。结果 67例患者中,VG检出61例,获得与光学胃镜相似图像,并经大体标本证实,其检出率(61/67,91.04%)与轴位CT的检出率(56/67,83.58%)差异无统计学意义(P=0.227)。对于胃癌灶≤3 cm的23例患者,VG检出20例(20/23,86.96%),高于轴位图像的13例(13/23,56.52%,P=0.016)。结论 采用MSCT行VG能检出胃癌,可获得与光学胃镜相似的图像;检出小胃癌病灶优于轴位CT,有望成为检出胃癌的辅助手段。
英文摘要:
      Objective To investigate value of multi-slice CT (MSCT) virtual gstroscogrphay (VG) and transverse CT in demonstration of gastric cancer in comparion with optical gastroscopy and pathology results. Methods Sixty-seven consecutive patients with gastric cancer confirmed or highly suspected by biopsy through optical gastrocopy underwent CT scanning after adequate stomach distention using gas-producing powder with MSCT, and VG images were obtained. Two experienced radiologists blinded to gastroscopy findings evaluated the transverse and VG images, respectively. Disagreements were resolved in consensus. The Results were compared with those of optical gastroendoscopy and gross pathological findings. Differences of detection rate of VG and transverse images for primary tumors were assessed with McNemar exact test. Results VG detected tumors in 61 out of 67 patients with a detection rate of 91.04% (61/67), while the detection rate of transverse CT was 83.58% (56/67). The difference was not statistically significant (P=0.227). Comparing with optical gastroendoscopy, VG got similar images to demonstrate morphologic characteristics of gastric cancers, which was confirmed at gross pathological examinations. In 23 patients with primary tumor diameter ≤3 cm, detection rate of VG was 86.96% (20/23), higher than that of transverse CT (56.52%, 13/23, P=0.016). Conclusion MSCT VG can visualize primary gastric cancer in the similar way with optical gastroendoscopy. For small lesions, VG is superior to transverse CT images and might be a promising modality for gastric cancer detection.
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