冯清华,罗良平,余江秀.实时组织弹性成像对乳腺良、恶性肿块诊断价值的Meta分析[J].中国医学影像技术,2011,27(2):321~325
实时组织弹性成像对乳腺良、恶性肿块诊断价值的Meta分析
Diagnostic value of real-time tissue elastography in breast tumor: A Meta-analysis
投稿时间:2010-08-19  修订日期:2010-10-23
DOI:
中文关键词:  弹性成像技术  超声检查  乳腺肿瘤  Meta分析
英文关键词:Elasticity imaging techniques  Ultrasonography  Breast neoplasms  Meta-analysis
基金项目:
作者单位E-mail
冯清华 暨南大学附属第一医院医学影像中心,广东 广州 510630  
罗良平 暨南大学附属第一医院医学影像中心,广东 广州 510630 tluolp@jnu.edu.cn 
余江秀 暨南大学附属第一医院医学影像中心,广东 广州 510630  
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中文摘要:
      目的 采用Meta分析评价实时组织弹性成像(RTE)对乳腺良、恶性肿块的诊断价值。方法 检索1994—2010年国内外公开发表的有关RTE诊断乳腺肿瘤的中文、英文文献,按照诊断试验的纳入和排除标准筛选文献,提取纳入研究的特征信息,进行Meta分析。结果 共纳入12篇文献,RTE对乳腺良、恶性肿块诊断的敏感度为0.78~0.89,特异度为0.84~1.00。合并敏感度和特异度分别为0.82(95%CI 0.79~0.85)、0.95(95%CI 0.93~0.96);合并阳性和阴性似然比分别为14.16(95%CI 8.38~23.93)、0.20(95%CI 0.17~0.23);SROC曲线下面积为0.91±0.01。结论 RTE对乳腺良恶性肿块的鉴别诊断具有较高的临床诊断价值。
英文摘要:
      Objective To evaluate meta-analysis in assessing the overall diagnostic value of real-time tissue elastography(RTE) in patients with breast tumor. Methods Relevant Chinese and foreign articles about RTE for assessing diagnostic accuracy of breast tumor were collected from the literatures published from 1994 to 2010. Meta-analysis was conducted. Results Twelve articles were selected. The reported sensitivities ranged from 0.78 to 0.89, and the specificities ranged from 0.84 to 1.00. The pooled sensitivity and specificity was 0.82 (95%CI 0.79—0.85) and 0.95 (95%CI 0.93—0.96), respectively, while the pooled positive and negative likelihood ratio was 14.16 (95%CI 8.38—23.93) and 0.20 (95%CI 0.17—0.23), respectively. The area under the curve of the summary receiver operating characteristic was 0.91±0.01. Conclusion RTE has medium to high value in the diagnosis of breast cancer.
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