| 陈少伯,姜铁民,梁国庆,赵季红,李玉明.血管内超声虚拟组织学成像对比分析急性心肌梗死相关动脉自发性再通与无再通[J].中国医学影像技术,2011,27(2):304~307 |
| 血管内超声虚拟组织学成像对比分析急性心肌梗死相关动脉自发性再通与无再通 |
| Comparative analysis of spontaneous reperfusion and non-spontaneous reperfusion of infarct-related arteries with visual histology intravascular ultrasound in acute myocardial infarction |
| 投稿时间：2010-07-09 修订日期：2010-10-10 |
| DOI： |
| 中文关键词: 心肌梗死 自发性再通 超声检查,介入性 虚拟组织学 |
| 英文关键词:Myocardial infarction Spontaneous reperfusion Ultrasonography, interventional Visual histology |
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| 中文摘要: |
| 目的 分析急性心肌梗死自发性再通和无再通患者梗死相关动脉的虚拟组织学特点,探讨斑块物理性状对自发性再通的作用机制。方法 急性ST段抬高性心肌梗死患者63例,根据冠状动脉造影心肌梗死溶栓试验(TIMI)血流分级,分为自发性再通组(21例)及无再通组(42例)。冠状动脉造影后,对梗死相关动脉进行血管内超声检查(IVUS),保存灰阶图像及虚拟组织学数据,分析斑块的虚拟组织学特点。结果 自发性再通组与无再通组残余管腔面积(LA)、斑块面积(PA)、斑块面积百分比(PAV)、斑块偏心指数(EI)及血管重构指数(RI)差异均有统计学意义(P均＜0.05)。两组患者纤维脂肪性斑块(FF)、钙化性斑块(DC)、坏死组织(NC)的面积及NC/DC比值差异亦均有统计学意义(P均＜0.05)。结论 急性心肌梗死自发性再通患者与非再通患者梗死相关动脉的斑块虚拟组织学特点有所不同,非再通患者斑块负荷更大,坏死组织成份更多。斑块的物理性状可影响自发性再通的发生率。 |
| 英文摘要: |
| Objective To analyze the characteristics of spontaneous reperfusion (SR) and non spontaneous reperfusion (NSR) of infarct-related arteries in acute myocardial infarction (AMI) patients with visual histology intravascular ultrasound (VH-IVUS), and to assess the effect of physical properties on spontaneous reperfusion. Methods Totally 63 patients with ST segment elevation AMI were divided into SR group (n＝21) or NSR group (n＝42) according to the grade of thrombolysis in myocardial infarction (TIMI). Intravascular ultrasound (IVUS) was performed on infarct-related arteries after coronary angiography. The gray scale images and the visual histology data were recorded, and the visual characteristics of plaques were analyzed. Results There were statistical differences of lumen area (LA), plaque area (PA), percent atheroma volume (PAV), plaque eccentricity index (EI) and remodeling index (RI) between SR and NSR group (all P＜0.05). Moreover, statistical differences of the area in fibro-fatty (FF), dense calcium (DC), necrotic core (NC) of the plaque and the value of NC/DC were found between the two groups (all P＜0.05). Conclusion The characteristics of visual hitology in SR group and NSR group are different. The area of NC is larger in NSR group than that in SR group. The physical features of atheroma plaque can influence the incidence of SR of infarct-related arteries. |
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