| 张旭初,王荣福,张春丽,左力.放射性核素肾动态显像测定肾移植供体肾小球滤过率[J].中国医学影像技术,2011,27(1):162~166 |
| 放射性核素肾动态显像测定肾移植供体肾小球滤过率 |
| Evaluation of radionuclide renal dynamic imaging in determination of glomerular filtration rate in kidney donors |
| 投稿时间：2010-10-23 修订日期：2010-11-15 |
| DOI： |
| 中文关键词: 肾小球滤过率 肾移植 放射性核素 肾动态显像 双血浆法 |
| 英文关键词:Glomercular filtration rate Kidney transplant Radionuclide Renal dynamic imaging Dual plasma sampling method |
| 基金项目:国家重点基础研究发展计划(973计划)(2006CB705705)、国家自然科学基金(30870729、81071183/H1806)。 |
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| 中文摘要: |
| 目的 评价放射性核素肾动态显像测定潜在肾移植供体(正常人)肾小球滤过率(GFR)的准确性。方法 对45名受检者行放射性核素肾动态显像和双血浆法测定肾脏GFR,以双血浆法为标准比较二者测定结果。结果 放射性核素肾动态显像测得的GFR(gGFR)与双血浆法测得的GFR(tGFR)高度相关(r=0.88,P<0.01),直线回归方程为gGFR=0.66tGFR+21.78,gGFR落在tGFR±15%、tGFR±30%和tGFR±50%范围内的受检者百分比分别为60.78%,89.56%和100%,gGFR与tGFR的偏差中位数为-1.23 ml/1.73(m2·min),绝对偏差中位数分别为10.78 ml/1.73(m2·min)。结论 在肾移植供体的筛选过程中,放射性核素肾动态显像可以提供准确的总肾及分肾GFR。 |
| 英文摘要: |
| Objective To evaluate renal dynamic imaging in determination of glomerular filtration rate (GFR) in potential kidney donors. Methods gGFR and tGFR of 45 normal adults were estimated by using radionuclide renal dynamic imaging and dual plasma sampling method respectively. Results gGFR correlated well with tGFR (r=0.88, P<0.01). The linear regression equation was gGFR=0.66tGFR+21.78. For gGFR, the 15%, 30% and 50% accuracy of tGFR was 60.78%,89.56% and 100%. The median of difference and absolute difference between tGFR and gGFR was -1.23 ml/(1.73 m2) and 10.78 ml/(1.73 m2), respectively. Conclusion Radionuclide renal dynamic imaging is an accuracy method for obtaining GFR of potential kidney donors. |
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