苏富勇,孙爱君,刘健,李家敏,杜静波.双时相PET显像诊断胃癌术后复发与转移[J].中国医学影像技术,2011,27(1):108~111
双时相PET显像诊断胃癌术后复发与转移
Dual-phase 18F-FDG PET in the diagnosis of recurrence or metastasis of gastric cancer after surgery
投稿时间:2010-06-03  修订日期:2010-10-28
DOI:
中文关键词:  胃肿瘤  正电子发射型体层摄影术  18F 氟脱氧葡萄糖  放射性核素显像
英文关键词:Stomach neoplasms  Positron-emission tomography  Fluorodeoxyglucose F18  Radionuclide imaging
基金项目:
作者单位E-mail
苏富勇 济南市106医院影像科,山东 济南 250022 sufuyong28@yahoo.com.cn 
孙爱君 淄博万杰医院PET中心,山东 淄博 255200  
刘健 淄博万杰医院PET中心,山东 淄博 255200  
李家敏 淄博万杰医院PET中心,山东 淄博 255200  
杜静波 淄博万杰医院PET中心,山东 淄博 255200  
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中文摘要:
       目的 评价双时相18F-FDG PET在诊断胃癌术后复发与转移中的应用价值。方法 对55例胃癌术后患者行常规PET及延迟显像。结果 55例术后患者中,13例胃部显影,10例Ⅰ级摄取,延迟显像后6例摄取增高,常规显像与延迟显像平均最大标准摄取值(SUVmax)差异有统计学意义,SUV变化率(△SUV)为(37.3±24.6)%,局部复发病灶显像较常规显像多检出6例;局部复发并转移15例,均为Ⅱ、Ⅲ级摄取,延迟显像后摄取变化不明显,平均SUVmax与常规显像无差异;转移17例。CT共检出22例复发或转移。结论 双时相18F-FDG PET能较常规PET及CT更好地鉴别良性摄取、术后复发及转移,有效提高胃癌转移与复发的诊断准确率。
英文摘要:
      Objective To observe the value of dual-phase 18F-FDG PET in the diagnosis of recurrence or metastasis of gastric cancer after surgical resection. Methods Fifty-five patients with gastric cancer underwent routine and delayed-phase 18F-FDG PET after surgery. Results Thirteen of the 55 patients presented gastric absorption of 18F-FDG, with 10 showing absorption of grade Ⅰ and 6 showing increased absorption on delayed-phase imaging. Difference of SUV was statistically significant between them, △SUV=(37.3±24.6)%. Six patients with local recurrent gastric cancers were newly diagnosed with dual-phase PET, not with routine PET, and 1 was false positive in diagnosis. Fifteen patients with local recurrent and metastatic gastric cancers showed grade Ⅱ, Ⅲ absorption of 18F-FDG, there was no obvious change in absorption nor in SUV on delayed-phase tomography. Meanwhile, 17 patients had metastatic cancers. Only 22 patients with recurrent or metastatic gastric cancers were diagnosed with CT. Conclusion Compared with routine PET and CT, dual-phase PET is more powerful in differentiating benign gastric absorption, local recurrence and metastasis of gastric cancer, and is able to improve the diagnosis of recurrence and metastasis of gastric cancer.
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