| 何文娟,沈加林,许建荣,华小兰.128排CT灌注成像诊断脑血管疾病[J].中国医学影像技术,2011,27(1):41~44 |
| 128排CT灌注成像诊断脑血管疾病 |
| Diagnosis of cerebrovascular diseases with 128-detector CT |
| 投稿时间：2010-06-15 修订日期：2010-10-03 |
| DOI： |
| 中文关键词: 灌注成像 体层摄影术,X线计算机 缺血性脑血管病 |
| 英文关键词:Perfusion imaging Tomography, X-ray computed Ischemic cerebral vascular disease128排CT灌注成像诊断脑血管疾病 |
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| 中文摘要: |
| 目的 探讨128排CT全脑灌注成像在缺血性脑血管疾病中的临床应用价值。 方法 对40例拟诊为缺血性脑血管病的患者,均在发病24 h内行头颅CT平扫、头颅CT灌注(CTP)检查,在发病24~72 h内复查MR DWI。分别将CT检出的病灶和MRI检出的病灶与CTP结果相比较。 结果 40例患者中,常规CT平扫于17例患者中共发现20个病灶,CTP检出42个病灶。CTP较常规CT平扫多检出的22个病灶中,15个病灶表现为脑血流量(CBF)与脑血容量(CBV)均较健侧下降,对比剂平均通过时间(MTT)及达峰时间(TTP)均较健侧明显延长或不可测量;4个病灶CBF较健侧降低,CBV较健侧稍增加或维持正常;3个病灶表现为整个大脑半球MTT及TTP较健侧明显延长,CBF与CBV较健侧未见明显减低;复查MR DWI证实其中35个病灶CBF与CBV均下降的病灶发展为梗死灶。 结论 在缺血性脑血管病发病24 h时间窗内,与常规CT平扫相比,128排CT全脑灌注能明显提高脑缺血灶的检出率,对早期发现脑缺血灶和避免病灶漏诊具有重要价值。 |
| 英文摘要: |
| Objective To explore the value of whole-brain perfusion with 128-detector computed tomography (CT) in ischemic cerebrovascular diseases. Methods Fourty patients dignosed as ischemic cerebrovascular diseases underwent plain CT and CT perfusion (CTP) within 24 h after the onset of symtoms. Follow-up MR DWI were performed in 24—72 h after the onset of symtoms. Results Among the 40 patients, 20 lesions were detected with plain CT in 17 patients, and 42 lesions were detected with CTP. Among the 22 lesions missed in plain CT, reduced CBF, CBV and prolonged MTT, TTP were showed in 15 lesions, while CBF reduced and CBV prolonged in 4 lesions, MTT and TTP prolonged or no change in CBF and CBV in 3 lesions. Follow-up MR DWI confirmed that 35 lesions in which CBF and CBV reduced together developed to infarct foci. Conclusion Within 24 h after the onset of symtoms, whole-brain perfusion with 128-slice CT could increase the detectable rate of the ischemic lesions significantly, therefore has important value in early detection of ischemic lesions and avoiding omission of lesions. |
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