王晓怡,卢洁,李坤成,张苗,徐国庆,舒华.功能磁共振成像观察左颞前部在汉语听觉词加工中的机制[J].中国医学影像技术,2011,27(1):37~40 |
功能磁共振成像观察左颞前部在汉语听觉词加工中的机制 |
Functional MRI observation on auditory Chinese lexical processing mechanism in left anterior temporal lobe |
投稿时间:2010-06-18 修订日期:2010-11-18 |
DOI: |
中文关键词: 左颞前部 听觉 复述 语义判断 磁共振成像 |
英文关键词:Left anterior temporal lobe Auditory Repetition Semantic judgment Magnetic resonance imaging |
基金项目:北京市"十百千"卫生人才培养专项经费。 |
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中文摘要: |
目的 探讨左侧颞前部在汉语听觉信息加工中的作用机制。方法 应用3.0T磁共振成像系统与标准头线圈对15名健康志愿者(男5名,女10名)进行功能磁共振成像(fMRI)。要求受试者完成听觉复述任务和听觉语义危险判断任务。应用软件包AFNI分析两种听觉任务在左颞前部的任务功能定位及其差异。结果 正常成人听觉语义判断任务相比听觉复述任务更多激活左侧颞中回及颞下回前部,而听觉语音复述任务相比听觉语义判断任务更多激活左侧颞上回前部。结论 脑内存在左颞前部对汉语听觉语音语义信息加工的分离,颞上前部对语音分析更强,颞前中下部对语义分析更强。 |
英文摘要: |
Objective To explore the neural mechanism for auditory Chinese lexical processing in the left anterior temporal lobe (ATL) of the healthy participants with functional magnetic imaging (fMRI). Methods Fifteen right-handed healthy participants, including 5 males and 10 females, were asked to repeat the auditory words or judge whether the auditory items were semantically dangerous. AFNI was used to process fMRI data and localize functional areas and the difference in the anterior temporal lobe. Results The results revealed the phonological processing on auditory Chinese lexical information was located in the anterior superior temporal gyrus, and the semantic processing was located in the anterior middle temporal gyrus. There existed segregation between the phonological processing and the semantic processing of the auditory Chinese words. Conclusion There was the function of semantic integration in the ATL. Two pathways to semantic access include the direct pathway in the dorsal temporal lobe for repetition task and the indirect in ventral temporal lobe for semantic judgment task. |
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