| 牛刚,杨健,王蓉,于学文,郭佑民.腰椎间盘退变的磁共振T2 map定量研究[J].中国医学影像技术,2010,26(12):2325~2329 |
| 腰椎间盘退变的磁共振T2 map定量研究 |
| Quantitative assessment of lumbar intervertebral disk degeneration with MR T2 map |
| 投稿时间：2010-07-15 修订日期：2010-08-06 |
| DOI： |
| 中文关键词: 椎间盘退变 磁共振成像 横向弛豫时间 |
| 英文关键词:Intervertebral disk degeneration Magnetic resonance imaging T2 relaxation time |
| 基金项目: |
|
| 摘要点击次数: 1845 |
| 全文下载次数: 1054 |
| 中文摘要: |
| 目的 探讨T2 map成像定量评价早期腰椎间盘退变的价值。方法 对46名受试者行腰椎MR矢状位T2WI及正中矢状位T2 map成像,根据Pfirrmann标准将L1-S1椎间盘分级,并测量髓核及纤维环前后缘T2值。分别比较各级髓核和纤维环前后缘T2值,对髓核和纤维环前后缘T2值与年龄、退变分级的相关性进行分析。采用单因素方差分析和Pearson相关分析。结果 共计测量229个椎间盘:①各分级腰椎间盘髓核T2值随分级增高而减小,除Ⅳ级与Ⅴ级,余各级间差异均有统计学意义(P<0.05);②各分级腰椎间盘纤维环前缘T2值呈上升趋势,除Ⅰ级、Ⅱ级与Ⅳ级,余各级间差异均无统计学意义(P＞0.05);③腰椎间盘髓核T2值与受试者年龄呈显著负相关(P<0.01),纤维环前、后缘T2值与受试者年龄无明显相关性(P＞0.01)。结论 基于T2 map成像定量测定腰椎间盘髓核T2值的变化是一种无创评价椎间盘早期退变的方法。 |
| 英文摘要: |
| Objective To evaluate the clinical value of T2 map for detecting of lumbar intervertebral disk degeneration (IVDD). Methods Sagittal fast spin echo T2WI and T2 map were acquired with 1.5T MR in 46 participants. Disks from L1 to S1 were classified based on the Pfirrmann grading system. T2 value of all nucleus pulposus (NP), anterior and posterior annulus fibrosus (AF) were measured and their variances in different grades were analyzed with one-way ANOVA test. Correlations between T2 value of NP, AF and age, grades were analyzed with Pearson correlation test. Results Totally 229 disks were measured. ①T2 value of NP decreased while the IVDD grade increased except grade Ⅳ and Ⅴ, significant differences of T2 value of NP were found between other grades (P<0.05). ②T2 value of anterior AF increased with the increasing of IVDD grade, but there was no significant difference of T2 value of anterior AF between grade Ⅰ and Ⅱ, grade Ⅰ and Ⅳ, grade Ⅱ and Ⅳ (P＞0.05). ③Linear regression analysis between T2 value of NP and age revealed significant negative verse correlation (P<0.01), but there was no significant correlation between T2 value of neither anterior AF or posterior AF and age (P＞0.01). Conclusion T2 measurement of NP is a non-invasive and quantitative tool for detecting the IVDD in early stage based on T2 map. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
