| 张宏,彭芸,刘祖祥,李时莲,吕忠礼,田丽芳,朱捷,赵旭娜,陈敏.MRI及1H-MRS评估针灸治疗对肥胖儿童腹部脂肪和肝内脂质含量的影响[J].中国医学影像技术,2010,26(11):2127~2130 |
| MRI及1H-MRS评估针灸治疗对肥胖儿童腹部脂肪和肝内脂质含量的影响 |
| MRI and 1H-MRS in evaluation of the effects of acupuncture therapy on abdominal fat and hepatic fat content in obese children |
| 投稿时间：2010-06-02 修订日期：2010-08-29 |
| DOI： |
| 中文关键词: 儿童 针灸 皮下脂肪,腹部 腹腔内脂肪 肝内脂质含量 |
| 英文关键词:Child Acupuncture Subcutaneous fat, abdominal Intra-abdominal fat Hepatic fat content |
| 基金项目:北京市自然科学基金面上项目(7092091)、脑与认知科学国家重点实验室开放课题(08B06)。 |
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| 中文摘要: |
| 目的 应用MRI和1H-MRS评估针灸治疗对肥胖儿童腹部脂肪和肝内脂质含量的影响。方法 10例肥胖儿童(男7例,女3例)接受规律针灸治疗1个月,治疗前、后分别测量体质量、体质量指数(BMI)、腰围、臀围、腰臀比值(WHR)、腹部脂肪体积(应用MRI)及肝内脂质含量(应用1H-MRS)。结果 针灸治疗后患者的BMI较治疗前减少3.50%(P=0.005)。腹腔内脂肪(VAT)体积、腹部总脂肪(TAT)体积及腹腔内脂肪/皮下脂肪比值(V／S)均较治疗前减少(P均＜0.05)。体质量、腰围、臀围、WHR、腹部皮下脂肪(SAT)体积及肝内脂质含量(IHCL) 均较治疗前减少,但差异无统计学意义(P＞0.05)。针灸治疗前后腹部脂肪体积(SAT、VAT)与人体测量参数(体质量、BMI、腰围及臀围)显著相关,而肝内脂质含量(IHCL)与人体测量参数及腹部脂肪体积等指标之间均无相关性。结论 针灸治疗可以显著减少肥胖儿童的BMI及腹部脂肪体积,特别是腹腔内脂肪体积。 |
| 英文摘要: |
| Objective To evaluate the influence of acupuncture therapy on abdominal fat and hepatic fat content in obese children with magnetic resonance imaging (MRI) together with proton magnetic resonance spectroscopy (1H-MRS). Methods Ten obese children (seven boys and three girls) were recruited. The body weights, body mass index (BMI), waist circumferences, hip circumferences, waist-to-hip ratios (WHR), abdominal fat volume (assessed by MRI) and hepatic fat content (assessed by 1H-MRS) were measured before and after 1 month of regularly acupuncture therapy. Results BMIs reduced by 3.50% after 1 month of acupuncture therapy (P=0.005). Abdominal visceral adipose tissue (VAT) volume, abdominal total adipose tissue (TAT) volume and abdominal visceral to subcutaneous fat ratio (V/S) all decreased after therapy (P<0.05). Decreases in body weight, waist circumference, hip circumference, WHR, abdominal subcutaneous adipose tissue (SAT) volume and intrahepatic content of lipid (IHCL) were also observed, but no statistical difference was found (P＞0.05). Before and after acupuncture therapy, there was a significant correlation between the level of abdominal fat volume (SAT, VAT) and anthropometric parameters (weight, BMI, waist circumferences, hip circumferences). There was no statistically significant correlation of IHCL with anthropometric parameters and abdominal fat volume. Conclusion Acupuncture therapy can significantly reduce BMI and abdominal adipose tissue volume through reducing abdominal VAT content in obese children. |
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