| 刘晓伟,吴雅峰,李一丹.斑点追踪显像技术评价慢性血栓栓塞性肺动脉高压患者左心室扭转运动[J].中国医学影像技术,2010,26(11):2117~2119 |
| 斑点追踪显像技术评价慢性血栓栓塞性肺动脉高压患者左心室扭转运动 |
| Assessment of left ventricle twist using speckle tracking imaging in patients with chronic thromboembolic pulmonary hypertension |
| 投稿时间：2010-07-20 修订日期：2010-09-05 |
| DOI： |
| 中文关键词: 高血压,肺性 血栓栓塞 斑点追踪显像 心室功能,左 |
| 英文关键词:Hypertension, pulmonary Thromboembolism Speckle tracking imaging Ventricular function, left |
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| 中文摘要: |
| 目的 应用超声心动图斑点追踪显像技术(STI)初步评价重度慢性血栓栓塞性肺动脉高压(CTEPH)患者左心室扭转运动特征。 方法 选择31例重度CTEPH患者(CTEPH组)和26名健康志愿者(正常对照组),采集胸骨旁左心室基底水平、心尖水平短轴切面及心尖四腔心、两腔心切面图像。采用Simpson法计算左心室舒张末期和收缩末期容积(LVEDV、LVESV)、左心室射血分数(LVEF)、右心室射血分数(RVEF);分析短轴切面收缩期心内膜下、心外膜下心肌,计算左心室整体扭转角度。 结果 CTEPH组RVEF显著低于正常对照组(P＜0.01);CTEPH组的LVEDV、LVESV较正常对照组减低,但差异均无统计学意义(P均>0.05),两组LVEF差异无统计学意义(P>0.05)。重度CTEPH患者左心室基底部和心尖部整体峰值旋转角度、左心室整体扭转角度明显减低(P均<0.01);基底部心内膜下峰值旋转角度减低(P<0.01)。 结论 重度CTEPH患者左心室扭转功能受损,左心室圆周方向收缩功能障碍。 |
| 英文摘要: |
| Objective To evaluate left ventricular twist in patients with severe chronic thromboembolic pulmonary hypertension (CTEPH) using speckle tracking imaging (STI). Methods Thirty-one severe CTEPH patients (CTEPH group) and 26 normal controls (control group) were enrolled. Parasternal basal short axis view, apical short axis view, apical four-and two-chamber view of left ventricle were obtained respectively. Left ventricular end-diastolic volume (LVEDV), end-systolic volume (LVESV) and ejection fraction (LVEF, RVEF) were calculated with Simpson method. Peak systolic rotation of subendocardium and subepicardium on short axis images were analyzed and the twist angle of left ventricular was calculated. Results RVEF in CTEPH group was lower than that in control group (P＜0.01), LVEDV and LVESV were also lower than those in control group, but no difference was found (all P>0.05). LVEF had no difference between the two groups (P>0.05). Basal and apical peak rotation and twist angle of left ventricle decreased significantly in CTEPH group (all P<0.01), so did the basal rotation angle of subendocardium (P<0.01). Conclusion Left ventricular transmural twist function is damaged, and left ventricular systolic dysfunction is obstructed in the circumferential movement in severe CTEPH patients. |
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