王锦惠,门殿霞,于子芳,闫芳,李春敏,肖文丽,刘英,张烁.经阴道彩色多普勒超声观察子宫内膜及内膜下血流预测体外受精-胚胎移植中子宫内膜的容受性[J].中国医学影像技术,2010,26(10):1930~1932
经阴道彩色多普勒超声观察子宫内膜及内膜下血流预测体外受精-胚胎移植中子宫内膜的容受性
Transvaginal color Doppler ultrasonic measurement of endometrial and subendometrial vascularity in the prediction of endometrial receptivity during in vitro fertilization-embryo transfer treatment
投稿时间:2010-05-31  修订日期:2010-07-05
DOI:
中文关键词:  超声检查,多普勒,彩色  体外,受精  胚胎植入  子宫内膜容受性
英文关键词:Ultrasonography, Doppler, color  Fertilization in vitro  Embryo implantation  Endometrial receptivity
基金项目:太原市科技局科技兴市项目(0802055)。
作者单位E-mail
王锦惠 太原市第二人民医院超声诊断科,山西 太原 030002 huiusdept@163.com 
门殿霞 太原市第二人民医院超声诊断科,山西 太原 030002  
于子芳 太原市第二人民医院超声诊断科,山西 太原 030002  
闫芳 太原市第二人民医院超声诊断科,山西 太原 030002  
李春敏 太原市第二人民医院超声诊断科,山西 太原 030002  
肖文丽 太原市第二人民医院超声诊断科,山西 太原 030002  
刘英 太原市第二人民医院超声诊断科,山西 太原 030002  
张烁 太原市中心医院生殖中心,山西 太原 030009  
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中文摘要:
       目的 探讨经阴道彩色多普勒超声检测子宫内膜厚度、类型、内膜及内膜下血流分型、血流动力学参数对预测体外受精-胚胎移植(IVF-ET)中子宫内膜容受性的价值。方法 应用经阴道彩色多普勒超声,对120例接受IVF-ET的不孕症患者,于控制性超排卵人绒毛膜促性腺激素注射日进行子宫内膜厚度、类型、内膜及内膜下血流检测,比较不同子宫内膜类型、不同子宫内膜及内膜下血流分型的妊娠率差异及妊娠组与未妊娠组血流动力学参数的差异。结果 妊娠组与未妊娠组比较,子宫内膜厚度差异无统计学意义(P>0.05);子宫内膜回声为三线型者妊娠率高于非三线型者,差异有统计学意义(P<0.05);不同子宫内膜及内膜下血流分型间妊娠率比较,差异有统计学意义(P<0.05);妊娠组子宫内膜及内膜下血流搏动指数、阻力指数、收缩期与舒张期血流速度比值均明显低于未妊娠组,两组间比较差异有统计学意义(P<0.05)。结论 经阴道彩色多普勒超声检测子宫内膜类型、子宫内膜及内膜下血流分布类型、血流动力学参数,可以评估子宫内膜容受性,预测IVF-ET结局。
英文摘要:
      Objective To investigate the role of transvaginal color Doppler ultrasonic measurement of endometrial thickness, endometrial pattern, blood flow pattern and parameters of endometrial and subendometrial blood flows in the prediction of endometrial receptivity during in vitro fertilization-embryo transfer (IVF-ET) cycles. Methods One hundred and twenty patients undergoing IVF-ET cycles were recruited. Transvaginal color Doppler ultrasound examination was performed to determine endometrial thickness, endometrial pattern, the blood flow distribution patterns, pulsatility index (PI), resisitance index (RI), systolic/diastolic ratio (S/D) of endometrial and subendometrial blood flows on the day of human chorionic gonadotropin (HCG) injection. Pregnancy rates were compared between the groups with triplelined endometrium and non-triplelined endometrium, and among the groups with different blood flow distribution patterns in endometrium and subendometrium. The comparison of blood flow parameters were carried out between pregnancy group and non-pregnancy group. Results There was no significant difference (P>0.05) between the pregnant group and non-pregnant group in endometrial thickness. The pregnance rate was significantly higher in the group with triplelined endometrium than the group with non-triplelined endometrium (P<0.05). The pregnance rate in the different blood flow distribution patterns in endometrium and subendometrium had statistical difference (P<0.05). Patients in the pregnant group had lower PI, RI and S/D of endometrial and subendometrial blood flows than those in the non-pregnant group (P<0.05). Conclusion Endometrial pattern, endometrial and subendometria blood flows measured with transvaginal color Doppler ultrasound can be as reliable indicators to assess endometrial receptivity and to predict the pregnancy outcome.
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