| 米玉成,龚向阳,王浩初,樊树峰,陈邦文,何海青.磁共振弥散加权成像:正常宫颈与宫颈癌表观弥散系数[J].中国医学影像技术,2010,26(9):1742~1744 |
| 磁共振弥散加权成像:正常宫颈与宫颈癌表观弥散系数 |
| Diffusion weighted imaging: Apparent diffusion coefficient values of normal cervix and cervical cancer |
| 投稿时间：2010-01-21 修订日期：2010-05-20 |
| DOI： |
| 中文关键词: 宫颈肿瘤 弥散磁共振成像 表观弥散系数 |
| 英文关键词:Uterine cervical neoplasms Diffusion magnetic resonance imaging Apparent diffusion coefficient |
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| 中文摘要: |
| 目的 探讨磁共振弥散加权表观弥散系数(ADC)值是否可有效地定量区分正常宫颈、正常宫颈腔分泌物和宫颈癌。方法 对经活检或术后病理证实的34例宫颈癌患者及21名正常健康女性行常规MR及DWI,比较正常宫颈、正常宫颈腔分泌物和宫颈癌的ADC值。结果 正常宫颈DWI表现为内、中、外带三层结构,平均ADC值分别为(1.41±0.26)×10－3 mm2/s、(1.38±0.32)×10－3 mm2/s、(1.40±0.16)×10－3 mm2/s;正常宫颈腔分泌物平均ADC值为(1.45±0.27)×10－3 mm2/s;宫颈癌平均ADC值为(1.05±0.14)×10－3 mm2/s,宫颈癌平均ADC值明显小于宫颈各层及宫颈腔分泌物平均ADC值(P＜0.05),宫颈内、中、外带及宫颈腔分泌物平均ADC值差异无统计学意义。结论 ADC值可有效地定量区分宫颈癌与正常宫颈、宫颈腔分泌物,但无法有效区分正常宫颈三层结构及宫颈分泌物。 |
| 英文摘要: |
| Objective To investigate whether values of apparent diffusion coefficient (ADC) can quantitatively differentiate cervical cancer, normal cervix of uterus and secretion of normal cervix. Methods Routine MRI and transversal diffusion weighted imaging (DWI) were performed in 34 patients with pathologically proved cervical cancer and 21 normal patients. Mean ADC values of normal cervix of uterus, secretion of cervix and cervical cancer were compared. Results Normal cervix of uterus in DWI manifested as inner, middle, outer bands, mean ADC values were (1.41±0.26)×10－3 mm2/s, (1.38±0.32)×10－3 mm2/s, and (1.40±0.16)×10－3 mm2/s, respectively. Mean ADC value in cervical secretion was (1.45±0.27)×10－3 mm2/s. There was no statistical difference among three bands of cervix and between normal cervix and cervical secretion . Mean ADC value in cervical cancer was (1.05±0.14)×10－3 mm2/s, which was lower than that of normal cervix and secretion of cervix (P＜0.05). Conclusion ADC value can not differentiate three bands of normal cervix and cervical secretion from each other, but can be used to quantitatively discriminate cervical cancer from normal cervix and cervical secretion. |
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