任卫东,刘爽,马春燕,晏楠,李秀云,肖杨杰.二维斑点追踪技术评价心脏再同步化治疗对左心房功能的影响[J].中国医学影像技术,2010,26(9):1704~1707
二维斑点追踪技术评价心脏再同步化治疗对左心房功能的影响
Evaluation of impact of cardiac resynchronization therapy on left atrial function with two-dimensional speckle tracking echocardiography
投稿时间:2010-04-13  修订日期:2010-05-03
DOI:
中文关键词:  超声心动描记术  心脏辅助装置  心房功能,左
英文关键词:Echocardiography  Heart-assist devices  Atrial function, left
基金项目:辽宁省自然科学基金(20082106)、辽宁省教育厅科学技术研究基金(2008748)。
作者单位E-mail
任卫东 中国医科大学附属盛京医院超声科,辽宁 沈阳 110004 moshengrenzzz@163.com 
刘爽 中国医科大学附属第一医院心功能科,辽宁 沈阳 110001  
马春燕 中国医科大学附属第一医院心功能科,辽宁 沈阳 110001  
晏楠 大众医院超声科,辽宁 沈阳 110000  
李秀云 中国医科大学附属盛京医院超声科,辽宁 沈阳 110004  
肖杨杰 中国医科大学附属盛京医院超声科,辽宁 沈阳 110004  
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中文摘要:
      目的 采用超声二维斑点追踪技术(STE)评价心脏再同步化治疗(CRT)后患者的左心房功能,探讨其临床应用价值。 方法 接受CRT的心力衰竭患者49例,在术前3天及术后3个月应用Simpson法计算左心房被动射血分数(LAPEF)和主动射血分数(LAAEF),采用STE检测左心房侧壁及房间隔收缩期应变率(SRs-LA、SRs-IAS)、舒张早期应变率(SRe-LA、SRe-IAS)、舒张晚期应变率(SRa-LA、SRa-IAS),同时测量左心室收缩末容积(LVESV)和射血分数(LVEF)。将术后LVESV减小率(ΔLVESV)≥15%定义为CRT短期治疗有效。 结果 CRT术后3个月的27例患者(55.10%)CRT短期治疗有效(R组)。术前R组患者的所有参数与无效患者比较差异无统计学意义,术后参数与无效患者比较,R组患者的LVESV减小,LVEF增大,LAPEF、LAAEF增加,SRs-LA、SRe-LA、SRa-LA、SRs-IAS、SRe-IAS、SRa-IAS明显增加(P均<0.05)。 结论 CRT短期可明显改善左心房功能;STE能准确评价左心房功能。
英文摘要:
      Objective To evaluate the impact on left atrial function with two-dimensional speckle tracking echocardiography (STE) in patients after cardiac resynchronization therapy (CRT). Methods Forty-nine heart failure patients scheduled for CRT were included. STE was performed 3 days before and 3 months after the pacemaker implantation. Left atrial passive ejection fraction (LAPEF) and left atrial active ejection fraction (LAAEF) were calculated with Simpson method. Peak systolic stain rate (SRs-LA, SRs-IAS), peak early diastolic stain rate (SRe-LA, SRe-IAS) and peak late diastolic strain rate (SRa-LA, SRa-IAS) on the interatrial septum and the lateral wall of the left atrium using speckle tracking echocardiography were analyzed. LV end-systolic volume (LVESV) and left ventricular ejection fraction (LVEF) were also measured. Patients were divided into responders and non-responders, based on a reduction ≥15% in LVESV after CRT. Results Twenty-seven patients (55.10%) were classified as responders. Compared with non-responders, there was no difference in preoperative state, while the responders demonstrated a significant increase of LVEF, LAPEF, LAAEF, SRs-LA, SRs-IAs, SRe-LA, SRe-IAs, SRa-LA, SRa-IAs on the interatrial septum and the lateral wall of the left atrium, and LVESV decreased (all P<0.05). Conclusion CRT can promptly increase the left atrial function. STE are readily obtained parameters that provide unique data about atrial function.
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