| 赵莹,黄道中,黄小莉.超声造影鉴别诊断甲状腺结节良恶性的价值[J].中国医学影像技术,2010,26(8):1441~1443 |
| 超声造影鉴别诊断甲状腺结节良恶性的价值 |
| Value of contrast-enhanced ultrasonography in differential diagnosis of benign or malignant thyroid nodules |
| 投稿时间：2010-03-23 修订日期：2010-05-11 |
| DOI： |
| 中文关键词: 甲状腺结节 超声检查 造影剂 时间-强度曲线 |
| 英文关键词:Thyroid nodule Ultrasonography Contrast media Time-intensity curve |
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| 中文摘要: |
| 目的 探讨超声造影对鉴别诊断甲状腺结节良恶性的价值。方法 回顾性分析39个甲状腺结节的彩色多普勒血流显像及超声造影灌注过程,观察病灶周边及内部造影剂灌注强度,通过时间-强度曲线分析,比较病灶周边感兴趣区(ROI)峰值强度(PI)与达峰时刻病灶内部ROI相对应的造影剂灌注强度(II)的差异程度,计算两者差值△I及诊断良、恶性结节的△I分界值。结果 甲状腺恶性结节造影增强模式多为弥漫性整体增强(94.12%),良性结节多为周边先于内部增强(86.36%),并以周边环状增强为主,内部轻微增强或始终无增强。初步界定△I＞6.08 dB时,良性结节可能性大,敏感度为85.71%;△I＜2.89 dB时,恶性结节可能性大,敏感度为82.35%。结论 超声造影对鉴别甲状腺结节的良恶性有一定实用价值。 |
| 英文摘要: |
| Objective To investigate the value of contrast-enhanced ultrasonography (CEUS) in the differential diagnosis of benign or malignant thyroid nodules. Methods Color Doppler flow imaging (CDFI) and contrast- enhanced ultrasonography perfusion of 39 thyroid nodules were retrospectively analyzed. The filling intensity of both periphery and interior of the nodule by the time-intensity curve (TIC) was observed. The evaluated parameters included peak intensity (PI) of the periphery, interior intensity (II) at the PI time, the difference of PI and I (△I). Then the diagnostic cut-of points for thyroid benign or malignant thyroid nodules was calculated. Results Most of the malignant thyroid nodules were filled SonoVue pervasively (94.12%). Most of the benign thyroid nodules showed early wash in of the periphery (86.36%), and the majority showed ring enhancement at periphery, slight or none enhancement in interior. It was prone to benign nodule when △I>6.08 dB, and the sensitivity was 85.71%. Simultaneously, it was prone to malignant nodule when △I<2.89 dB and the sensitivity was 82.35%. Conclusion CEUS is valuable in the differential diagnosis of benign or malignant thyroid nodules. |
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