张音佳,陈悦,黄国英.斑点追踪技术评价肥厚型心肌病左心室肌扭转运动[J].中国医学影像技术,2010,26(6):1057~1060
斑点追踪技术评价肥厚型心肌病左心室肌扭转运动
Speckle tracking imaging assessment of left ventricular torsion in patients with hypertrophic cardiomyopathy
投稿时间:2009-12-12  修订日期:2010-02-11
DOI:
中文关键词:  超声心动描记术  心肌病,肥厚性  心室功能,左  斑点追踪显像
英文关键词:Echocardiography  Cardiomyopathy, hypertrophic  Ventricular function, left  Speckle tracking imaging
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作者单位E-mail
张音佳 复旦大学附属儿科医院心血管中心,上海 201102
复旦大学附属华东医院超声科,上海 200040 
 
陈悦 复旦大学附属华东医院超声科,上海 200040  
黄国英 复旦大学附属儿科医院心血管中心,上海 201102 gyhuang@shmu.edu.cn 
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中文摘要:
       目的 应用斑点追踪技术研究肥厚型心肌病的左心室肌的旋转运动及扭转特征。方法 病例组为24例非对称性肥厚型心肌病患者,其中室间隔和左心室前、侧壁增厚归为病例组1,室间隔中上部肥厚归为病例组2;正常对照组为48名健康志愿者。采用GE Vivid 7超声诊断仪,采集左心室短轴二尖瓣水平、乳头肌水平、心尖水平二维图像,脱机分析得到不同水平、不同节段的旋转角度、旋转速度及扭转角度,计算舒张早期解旋率。结果 病例组乳头肌水平旋转角度较正常对照组趋向于逆时针方向,且病例组2与正常对照组差异有统计学意义(P<0.05);二尖瓣水平和心尖水平旋转运动三组间差异无统计学意义(P>0.05)。病例组1、病例组2与正常对照组左心室舒张早期解旋率分别为(0.22±0.11)%/ms、(0.23±0.08)%/ms、(0.43±0.19)%/ms,病例组1和病例组2均较正常对照组降低(P<0.05)。结论 肥厚型心肌病不同的表现型其左心室扭转及旋转运动表现不同;应用斑点追踪技术可以准确地评价肥厚型心肌病患者的左心室扭转及旋转运动。
英文摘要:
      Objective To assess the left ventricular (LV) rotation and torsion in patients of hypertrophic cardiomyopathy (HCM) with two-dimensional ultrasound speckle-tracking imaging. Methods Twenty-four patients with asymmetrical HCM (study group) were divided into 2 subgroups: the hypertrophic segments involved interventricular septum, anterior wall and lateral wall (study group 1) and the superior and middle part of septum (study group 2). A total of 48 healthy subjects were selected as control group. GE Vivid 7 was used to obtain two-dimensional short-axis images at the level of mitral valve, papillary muscle and apex. Then the rotation angle, rotation velocity, torsion and untwisting rate were calculated with off-line analysis. Results Most segments of the middle short-axis tended to rotate counterclockwise in study group 1 and study group 2 compared with control group, but statistical difference was only found between study group 2 and control group (P<0.05). In basal and apical LV short-axis, there was no statistical difference in rotation displacement in most segments. Untwisting rates were (0.22±0.11)%/ms in study group 1, and (0.23±0.08)%/ms in study group 2, both lower than that in control group ( %/ms, P<0.05). Conclusion Difference phenotype in patients with HCM may show different pattern of rotation and torsion. Speckle tracking imaging can evaluate LV rotation and torsion in patients with HCM conveniently.
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