| 刘于宝,梁长虹,张忠林,王秋实,谢淑飞,余元新,刘再毅.3.0TMR弥散加权成像评价肝细胞癌射频消融治疗疗效[J].中国医学影像技术,2010,26(5):896~899 |
| 3.0TMR弥散加权成像评价肝细胞癌射频消融治疗疗效 |
| Evaluation on the therapeutic effect of radiofrequency ablation of HCC with 3.0T MR diffusion weighted imaging |
| 投稿时间：2010-01-05 修订日期：2010-02-03 |
| DOI： |
| 中文关键词: 癌,肝细胞的 导管消融 扩散磁共振成像 |
| 英文关键词:Carcinoma, hepatocellular Catheter ablation Diffusion magnetic resonance imaging |
| 基金项目:广东省医学科学技术研究基金(A2009018)、广东省科技计划项目(2007B031515008)。 |
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| 中文摘要: |
| 目的 评价3.0T MR表观弥散系数(ADC)检测射频消融治疗后肝细胞癌(HCC)变化的价值,探讨弥散加权成像(DWI)在检测HCC射频消融治疗后不同病理改变的价值。方法 40例HCC患者在射频消融治疗后3~7天、2个月、6个月接受3.0T MR DWI检查,b值为600 s/mm2,测量、分析射频消融治疗后病灶ADC值。结果 射频消融治疗后3~7天、2个月、6个月坏死区ADC值明显降低,2个月、6个月时射频消融中心坏死区ADC值高于治疗后3~7天;3~7天与2个月、6个月时坏死组织的ADC值比较,差异均有统计学意义(P<0.01),治疗后2个月与6个月时坏死组织的ADC值差异无统计学意义(P>0.05)。治疗后3~7天、2个月、6个月时活性残留或复发肿瘤组织ADC值差异均无统计学意义(P>0.05)。结论 ADC值可用于鉴别射频消融治疗HCC后坏死组织与复发或残留肿瘤组织。 |
| 英文摘要: |
| Objective To evaluate the value of ADC in detecting the lesions of post-radiofrequency ablation of hepatocellutar carcinoma (HCC) with 3.0T MR DWI, and the value of 3.0T DWI in detecting features of HCC. Methods Forty patients with HCC of post-radiofrequency ablation 3—7 d, 2 months, 6 months underwent 3.0T MR DWI (b=600 s/mm2). The ADC values of lesions pre- and post-radiofrequency ablation were measured and analyzed. Results The ADC values of necrosis tissues decreased evidently in 3—7 d, 2 months, 6 months, and the values of necrosis tissues in 2 months and 6 months were higher than those of 3-7 d. There were significant differences of ADC values between 3—7 d and 2 months, as well as 3-7 d and 6 months (P<0.01), but no significant differences of ADC values was found between 2 months and 6 months (P>0.05). There was no significant difference of ADC values of tumors in the viable residue or recurrence tumor tissues among 3-7 d, 2 months, 6 months (P>0.05). Conclusion The ADC values of 3.0T MR DWI can be used in distinguishing the necrosis tissues and the viable residue or recurrence tumor tissues in HCC after radiofrequency ablation. |
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