| 吴晶,赵文清,孙吉林,吴杰,李素敏.磁源性影像在癫痫患者术前听觉性语言区定位中的应用[J].中国医学影像技术,2010,26(3):452~455 |
| 磁源性影像在癫痫患者术前听觉性语言区定位中的应用 |
| Localization of linguistic center of auditory function in presurgical epileptic patients with magnetic source imaging |
| 投稿时间：2009-10-15 修订日期：2009-12-09 |
| DOI： |
| 中文关键词: 语言 癫痫 磁源性影像 脑磁图描记术 |
| 英文关键词:Language Epilepsy Magnetic source imaging Magnetoencephalography |
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| 中文摘要: |
| 目的 探讨磁源性影像在癫痫患者术前语言区定位中的应用。方法 应用磁源性影像技术对24例癫痫患者手术前行癫痫灶定位及听觉性语言区定位,并确定癫痫灶与听觉性语言区的关系。结果 24例患者中,听觉性语言中枢位于左颞叶14例,右颞叶5例,双侧颞叶5例。癫痫灶位于左颞叶14例,左颞顶叶1例,右颞叶4例,右颞顶叶1例,左额颞叶1例,右额颞顶叶1例,双侧颞叶2例。10例癫痫灶与听觉性语言中枢重叠,10例癫痫灶与听觉性语言中枢所在位置不重叠,3例癫痫灶位于语言区前方,1例癫痫灶位于语言区后方。1例患者因左颞叶胚胎发育不良性神经上皮瘤与听觉性语言区重叠未能全部切除,术后出现短期语言功能障碍,术后随访仍偶有幻听,其余患者均无语言功能障碍发生。结论 磁源性影像可对癫痫患者进行癫痫灶定位及语言区定位,对减少手术后语言功能障碍具有重要意义。 |
| 英文摘要: |
| Objective To assess the value of magnetic source imaging (MSI) in localizing the linguistic center of auditory function of epileptic patients before operation. Methods Epileptic focus and the linguistic center of auditory function in 24 patients were localized with MSI before operation. And the relationship between epileptic focus and auditory language area was observed. Results The linguistic center of auditory function was localized in left temporal lobe in 14 patients, in right temporal lobe in 5 patients and in bilaterial temporal lobe in 5 patients. Epileptic focus was localized in left temporal lobe in 14 patients, in left temporal lobe and left parietal lobe in 1 patient, in right temporal lobe in 4 patients, in right temporal lobe and parietal lobe in 1 patient, in left frontal lobe and left temporal lobe in 1 patient, in right frontal lobe, right temporal lobe and parietal lobe in 1 patient, and in bilaterial temporal lobe in 2 patients. Epileptic focus was superimposed with the linguistic center of auditory function in 10 patients, while was not superimposed with the linguistic center of auditory function in 10 patients. The epileptic focus was localized in front of the linguistic center of auditory function in 3 patients, in behind of the linguistic center of auditory function in 1 patient. The lesion of the patient suffered from dysembryoplastic neuroepithelial tumor was not excised completely because the epileptic focus was superimposed with the linguistic center of auditory function, and the patient appeared language functional disturbance after operation in short period, remaining auditory hallucination occasionally after operation. Conclusion Epileptic focus and the linguistic center of auditory function can be localized accurately and the relationship between them can be observed clearly with MSI. MSI is useful to reduce the occurrence of language disturbance after operation. |
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