侯敏,吕国荣,唐力.多普勒超声检测大脑中动脉收缩期峰值流速与胎儿贫血[J].中国医学影像技术,2010,26(2):310~312
多普勒超声检测大脑中动脉收缩期峰值流速与胎儿贫血
Doppler ultrasonography in detection of middle cerebral artery peak systolic velocity for the diagnosis of fetal anemia
投稿时间:2009-06-23  修订日期:2009-09-17
DOI:
中文关键词:  超声检查,多普勒  大脑中动脉  收缩期峰值流速  胎儿  贫血
英文关键词:Ultrasonography, Doppler  Middle cerebral artery  Peak systolic velocity  Fetus  Anemia
基金项目:
作者单位E-mail
侯敏 福建医科大学附属第二医院超声科,福建 泉州 362000  
吕国荣 福建医科大学附属第二医院超声科,福建 泉州 362000 lgr_feus@sina.com 
唐力 福建医科大学附属第二医院超声科,福建 泉州 362000  
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中文摘要:
      目的 采用多普勒超声测量胎儿大脑中动脉收缩期峰值流速(MCA-PSV),并探讨其与胎儿贫血的关系。方法 检测535名孕14~40周正常胎儿的MCA-PSV,建立标准值。以MCA-PSV>相同孕周均数+2个标准差或1.5×相同孕周均数为标准,对MCA-PSV异常增高的胎儿进行评价。结果 胎儿MCA-PSV与孕周呈线性正相关,线性回归方程为:MCA-PSV=-9.955+1.561×孕周。以不同孕周胎儿MCA-PSV均数+2个标准差作为筛查胎儿贫血标准,在209例针对性产科超声检查中共筛查出7例,其中4例MCA-PSV>相同孕周正常胎儿均数的1.5倍,经引产证实为严重胎儿贫血。结论 胎儿MCA-PSV高于1.5倍相同孕周均数可作为产前超声筛查胎儿贫血的一个重要提示指标。
英文摘要:
      Objective To detect the normal value of the fetal middle cerebral artery peak systolic velocity (MCA-PSV) with Doppler ultrasonography, and to investigate the association between MCA-PSV and fetal anemia. Methods Doppler ultrasonography was performed in 535 normal pregnant women from the 14th to the 40th week of gestation. MCA-PSV was measured, and the standard value of the normal fetal MCA-PSV was established. Fetuses with abnormal high MCA-PSV were assessed with a standard of MCA-PSV>mean vale of gestational weeks+2 standard deviation or 1.5 multiples of mean value of gestational weeks. Results The value of normal fetal MCA-PSV correlated well with the gestational weeks (linear regression equation was: MCA-PSV=-9.955+1.561×weeks; r=0.795, P<0.0001). Using 1.5 multiples of the mean of different gestational weeks to diagnose the moderate and severe fetal anemia, 7 fetuses were screened out of 209 of obstetric ultrasonography; 4 of them had MCA-PSV>1.5 multiples of mean value of gestational weeks and were proved with induced labor. Conclusion The value of 1.5 multiples of mean value of gestational weeks of fetal MCA-PSV in prenatal ultrasonography might be an important clue for the diagnosis of fetal anemia.
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