| 马麒,单玉喜,方军初,阳东荣,谢芳.能量多普勒超声定量参数与前列腺结节血管生成的相关性[J].中国医学影像技术,2010,26(1):138~141 |
| 能量多普勒超声定量参数与前列腺结节血管生成的相关性 |
| Correlation between quantitative parameter in power Doppler ultrasonography and angiogenesis of prostate nodules |
| 投稿时间：2009-06-08 修订日期：2009-09-01 |
| DOI： |
| 中文关键词: 前列腺疾病 超声检查,多普勒 微血管密度 |
| 英文关键词:Prostate diseases Ultrasonography, Doppler Microvessel density |
| 基金项目:2008年苏州市社会发展指导计划基金(SZD0878)。 |
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| 中文摘要: |
| 目的 探讨经直肠能量多普勒超声(PDUS)定量参数与前列腺结节血管生成的相关性。方法 应用PDUS和彩色血流分析软件,记录73例患者共94个前列腺结节的峰值血流指数(PVI)。前列腺结节穿刺标本行CD34抗体染色,记录微血管密度(MVD),分析其与PVI的相关性。结果 移行区和周围区恶性结节组PVI、MVD均高于良性组(P＜0.05);PVI和MVD在恶性结节组呈正相关(r移行区＝0.76;r周围区＝0.79),移行区良性结节组无相关性(r=0.18),周围区良性结节组有相关性(r=0.44)。PVI鉴别移行区结节良恶性的敏感性和特异性分别为78.57%和80.77%,鉴别周围区结节良恶性的敏感性和特异性分别为62.07%和91.00%。结论 PDUS定量参数PVI能间接反映前列腺结节内血管生成的特征,为前列腺结节良恶性的鉴别提供了新的方法。 |
| 英文摘要: |
| Objective To explore the relationship between the quantitative parameter in transrectal power Doppler ultrasonography (PDUS) and angiogenesis of prostate nodules in pathology. Methods PDUS and the analytic software of color flow were used, and peak vascularization indexs (PVIs) of 94 prostate nodules in 73 patients were recorded. The biopsy specimen was stained with CD34 antibody, and the microvessel density (MVD) was calculated. The correlation between PVI and MVD was statistically analyzed. Results PVI and MVD of the malignant nodules, in both transition zone (TZ) and peripheral zone (PZ), were significantly higher than those of the benign nodules, respectively (P＜0.05). There was positive correlation between PVI and MVD of the malignant nodules (rTZ=0.76; rPZ=0.79), but no correlation between PVI and MVD was found in TZ of benign nodules (r=0.18), while there was correlation between PVI and MVD in PZ (r=0.44). In TZ, the sensitivity and speciality of differentiation malignant nodules from benign nodules were 78.57% and 80.77%, respectively, and in PZ they were 62.07% and 91.00%, respectively. Conclusion As a quantitative parameter in PDUS, PVI can indirectly reflect the angiogenesis of prostate cancerous nodules, providing a new method for differentiation malignant nodules from benign nodules. |
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