| 王余椿,刘晓晟,许建荣.CT、PET、PET/CT对肿瘤腹膜转移诊断价值的Meta分析[J].中国医学影像技术,2010,26(1):99~103 |
| CT、PET、PET/CT对肿瘤腹膜转移诊断价值的Meta分析 |
| CT, PET and PET/CT in diagnosing of peritoneal metastases: Meta analysis |
| 投稿时间：2009-06-05 修订日期：2009-09-30 |
| DOI： |
| 中文关键词: 腹膜转移 体层摄影术,发射型计算机 体层摄影术,X线计算机 Meta分析 |
| 英文关键词:Peritoneal metastases Tomography, emission-computed Tomography, X-ray computed Meta analysis |
| 基金项目:上海市重点学科(S30203)、上海交通大学医学院重点学科。 |
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| 中文摘要: |
| 目的 通过Meta分析评价CT、PET、PET/CT对腹膜转移的临床诊断价值。方法 收集2000年1月—2008年5月国内外公开发表的以病理学和(或)手术结果为金标准的关于CT、PET、PET/CT诊断腹膜转移的中英文文献。采用SAS 8.0、Meta-DiSc 1.4、STATA 10.0软件,检验异质性,根据异质性结果选择相应效应模型,计算出汇总灵敏度和汇总特异度,以综合受试者工作特性曲线(SROC)、曲线下面积(AUC)定性、定量评价该诊断方法的准确率。结果 11篇文献符合纳入标准,PET对腹膜转移诊断的汇总特异度最高 ,PET/CT的汇总灵敏度最高 ,PET、PET/CT和CT的AUC和Q*分别为0.92、0.85,0.99、0.96,0.91、0.84,PET/CT与CT的AUC值比较差异有统计学意义(Z=2.33,P<0.05)。结论 对肿瘤腹膜转移,PET/CT是一种准确性较高的无创性检查方法。 |
| 英文摘要: |
| Objective To assess the value of CT, PET, PET/CT in diagnosis of peritoneal metastases with Meta analysis. Methods Articles of CT, PET or PET/CT on peritoneal metastases published in English or Chinese from Jan 2000 to May 2008 were collected, and histopathological and (or) surgical findings were taken as golden standards. The sensitivity, specificity, summary receiver operating characteristic (SROC) curves, area under the curve (AUC) and the heterogeneity were calculated with software of SAS 8.0, Meta-DiSc 1.4 and STATA 10.0. Results The results of Meta analysis from 11selected articals showed that PET had the highest pooled specificity ; PET/CT had highest pooled sensitivity . The AUC and Q* of PET, PET/CT and CT was (0.92, 0.85), (0.99, 0.96), (0.91, 0.84), respectively. AUC of PET/CT was higher than that of CT (Z=2.33, P<0.05). Conclusion PET/CT is a high accuracy diagnostic tool for detecting peritoneal metastases. |
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