| 邢古生,王爽,欧阳汉,马霄虹,周纯武.CT与MRI增强扫描诊断肝细胞癌的对比分析[J].中国医学影像技术,2010,26(1):1~4 |
| CT与MRI增强扫描诊断肝细胞癌的对比分析 |
| Comparison of CT and dynamic-enhancement MRI for the diagnosis of hepatocellular carcinoma |
| 投稿时间：2009-09-21 修订日期：2009-10-08 |
| DOI： |
| 中文关键词: 肝肿瘤 体层摄影术,X线计算机 磁共振成像 诊断显像 |
| 英文关键词:Liver neoplasms Tomography, X-ray computed Magnetic resonance imaging Diagnostic imaging |
| 基金项目:"十一五"国家科技及支撑课题(2007BAI05B05)。 |
|
| 摘要点击次数: 2890 |
| 全文下载次数: 943 |
| 中文摘要: |
| 目的 比较多排螺旋CT三期增强及3.0T MR多期动态增强扫描对肝细胞肝癌(HCC)的诊断价值。方法 60例临床疑似HCC患者接受CT及MR检查,39例确诊为HCC,共59个病灶。CT采用平扫加三期增强,MR采用LAVA技术双动脉期、双门脉期、双静脉期及延迟期共7期动态增强扫描。对观测数据行Alternative-free-response ROC(AFROC)曲线分析,并计算曲线下面积(Az),比较两种方法的诊断价值。结果 CT增强扫描的Az平均值为0.8120±0.0118,MR多期动态增强扫描的Az平均值为0.9093±0.0072,差异无统计学意义。在＜1 cm的HCC病灶组,CT和MR增强扫描的平均灵敏度分别为63.89％和80.55％。在1~3 cm组和＞3 cm组,CT和MR增强扫描诊断的灵敏度差异均无统计学意义。在所有病灶中,CT多期增强扫描的灵敏度低于MR动态增强扫描(83.62% vs 88.70%),差异无统计学意义,CT阳性预测值(PPV)也低于MR扫描(93.07% vs 96.31%),差异无统计学意义。结论 在诊断HCC病灶方面,MR动态增强扫描与CT增强扫描相比差异无统计学意义;但对于小于1 cm病灶,MR动态增强扫描诊断的灵敏度显著高于CT增强扫描。 |
| 英文摘要: |
| Objective To compare the diagnostic ability of triple-phase CT and multiple-phase dynamic MR for patients with suspected hepatocellular carcinoma (HCC). Methods Triple-phase CT and multiple-phase dynamic MR scan were performed in 60 patients. Fifty-nine HCC lesions were confirmed in 39 patients. MR was performed with LAVA technique, the images included masks, dual-artery phases, dual-portal phases, dual-venous phases and delayed phase. Three observers separately evaluated the CT and MR imaging, and the results were compared with alternative-free-response ROC(AFROC)curve, the area under ROC (Az) was calculated to compare the diagnostic ability. Results The mean Az value of CT for the diagnosis of HCC was 0.8120±0.0118, of MR was 0.9093±0.0072 (P>0.05). In the group of HCC less than 1 cm in the diameter, the sensitivity of CT and MR was 63.89% and 80.55%(P＝0.013). In the groups HCCs of 1－3 cm and >3 cm, the sensitivity of CT and MR appeared no significant difference (P>0.05). Of all HCCs, the sensitivity of CT was lower than MR (83.62% vs 88.70%), but the difference was not significant (P>0.05). The positive predict value (PPV) of CT was also lower than MR (93.07% vs 96.31%, P>0.05). Conclusion The diagnostic ability of multiple-phase dynamic-enhancement MR scan for HCCs is similar to that of triple-phase enhancement CT. For HCC less than 1 cm in diameter, dynamic-enhancement MR is superior to that of contrast-enhancement CT scan, while for the larger ones, the difference is not significant. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
