| 史鹏丽,宋丹阳,史铁梅.实时灰阶超声造影鉴别宫腔良恶性病变的应用研究[J].中国医学影像技术,2009,25(S1):150~152 |
| 实时灰阶超声造影鉴别宫腔良恶性病变的应用研究 |
| Application of real-time gray scale contrast-enhanced ultrasonography in differentiation of benign and malignant diseases in uterine cavity |
| 投稿时间：2008-08-13 修订日期：2009-03-28 |
| DOI： |
| 中文关键词: 超声造影剂 时间-强度曲线 宫腔病变 |
| 英文关键词:Ultrasound contrast agent Time-intensity curves Diseases in uterine cavity |
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| 中文摘要: |
| 目的 探讨实时灰阶超声造影鉴别宫腔良恶性病变的临床应用价值。 方法 使用脉冲反向谐波成像技术对27例宫腔病变患者及8名正常内膜的妇女行实时灰阶超声造影检查,比较宫腔病变良性组、恶性组和正常对照组的造影增强模式及时间-强度曲线(TIC)形态和参数的差异。 结果 造影增强模式: 恶性组病灶内造影剂充盈模式呈快速整体充盈型(Ⅰ型),良性组及对照组均呈周围充盈型(Ⅱ型);TIC曲线形态:恶性组表现为"速升速降"型,波峰尖锐。良性组及对照组均表现为"速升缓降"型,波峰圆钝;造影参数中达峰时间、增强强度及AUC在良恶性组间、对照组和恶性组间比较差异均有统计学意义(P<0.05),良性组与对照组比较差异无统计学意义(P>0.05)。余造影参数在三组间比较差异均无统计学意义。达峰时间的ROC曲线下面积最大(0.903)。 结论 实时灰阶超声造影有助于宫腔病变良恶性的鉴别,具有一定的临床应用价值。 |
| 英文摘要: |
| Objective To assess the ability of real-time gray scale contrast-enhanced ultrasonography (CEUS) in revealing differences between benign and malignant diseases in uterine cavity. Methods Real-time gray scale CEUS was performed in 27 patients suspected diseases in uterine cavity and 8 normal controls, with pulse inversion harmonic imaging (PIH). Compared the contrast-enhanced patterns and time-intensity curves (TIC) analysis during the three groups. Results Contrast-enhanced patterns: endometrial cancers showed Grade Ⅰ; benign group and normal controls showed grade Ⅱ; shapes of TIC: The shapes of malignant group showed "quickly rising and quickly descending" with sharp peak and those of benign group and normal controls showed "quickly rising and slowly descending" with round peak; in contrast parameters, time to peak, rise intensity and area under curve (AUC) all had significant differences between benign group and malignant group, between normal controls and malignant group (P<0.05), and had no significant difference between benign group and normal controls (P>0.05). Other contrast parameters all had no significant difference during the three groups. The area under ROC curve of time to peak (0.903) of contrast parameters was the biggest. Conclusion Real-time gray scale CEUS may help for differentiating benign and malignant diseases in uterine cavity. |
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