| 李怀波,张振清,戴函碧,庄向荣,叶锋.肝癌患者介入治疗后长期生存的综合分析[J].中国医学影像技术,2009,25(12):2286~2289 |
| 肝癌患者介入治疗后长期生存的综合分析 |
| Comprehensive analysis of long-term survival of liver neoplasms patients after interventional therapy |
| 投稿时间：2009-07-07 修订日期：2009-07-23 |
| DOI： |
| 中文关键词: 肝肿瘤 介入治疗 远期疗效 |
| 英文关键词:Liver neoplasms Interventional therapy Long-term effect |
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| 中文摘要: |
| 目的 探讨影响肝癌患者介入治疗远期疗效的相关因素。方法 回顾性分析495例以经导管动脉化疗栓塞术(TACE)为主要治疗的肝癌患者的临床资料。按介入治疗后患者生存时间的不同分为≥5年组和<5年组,比较两组间影响患者生存期各因素间的差异。结果 31例患者生存5年以上,肿瘤内碘油沉积类型Ⅰ型者18例,Ⅱ型13例。495例患者5年、7年、10年的存活率分别为6.26％(31/495)、1.41％(7/495)和0.40％(2/495)。肿瘤分型、临床分期、血管造影表现、动静脉分流、碘油充填类型、扩散转移、肝功能因素、年龄、肿瘤直径、TACE治疗次数、TACE前后AFP值及其变化对肝癌介入治疗后长期生存存在影响(P均<0.05)。结论 肿瘤分型、患者自身状况、TACE治疗的质量、联合经皮无水乙醇消融(PEI)治疗、抗病毒治疗等因素对肝癌介入治疗的远期疗效有显著的影响。 |
| 英文摘要: |
| Objective To investigate the correlative factors influencing long-term efficacy of patients with liver neoplasms after interventional therapy. Methods A total of 495 patients underwent transcatheter arterial chemoembolization (TACE), and the data were retrospectively analyzed. The patients were divided into two groups according to the survival time after interventional therapy: ≥5 years and <5 years. Correlative factors were compared in both two groups. Results In 31 patients survived longer than 5 years, 18 patients with Lipiodol filling type Ⅰ tumor, and 13 with type Ⅱ tumor. The 5, 7, 10 years survival rate in all 495 patients was 6.26％ (31/495), 1.41％ (7/495) and 0.40％ (2/495), respectively. Factors including tumor pattern, clinical classification, the features of angiography, with or without heptic arteriovenous fistula, the pattern of Lipiodol filling, with or without invasion and metastasis, hepatic function, patient’s age, tumor diameter, AFP value before and after TACE, the variety of AFP value after TACE influenced the long-term survival rate after interventional therapies (P＜0.05). Conclusion The characteristics of tumor, patient’s status, the quality of TACE, whether combined with PEI, and/(or) anti-virus treatment have significant influence on long-term efficacy after interventional therapy in patients with liver neoplasms. |
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